배열형 섬광결정을 이용한 소형 감마카메라의 평행구멍형 조준기 최적화 연구 = Optimization of Parallel-Hole Collimator for Small Gamma Camera Based on Pixellated Crystal Array

다국어 초록 (Multilingual Abstract)

The purpose of this study is to optimize a parallel-hole collimator for small gamma camera having the pixellated crystal array and evaluate the effect of crystal-collimator misalignment on the image quality using a simulation tool GATE (Geant4 Application for Tomographic Emission). The spatial resolution and sensitivity were measured for the various size of hexagonal-hole and matched square-hole collimators with a Tc-99m point source and the uniformity of flood image was estimated as a function of the angle between crystal array and collimator by misalignment. The results showed that the spatial resolution and sensitivity were greatly improved by using the matched collimator and the uniformity was reduced by crystal-collimator misalignment.

참고문헌 (Reference)

1 정용현, "핵의학 영상연구를 위한 몬테칼로 모사코드" 대한핵의학회 42 (42): 127-136, 2008

2 정진호, "소동물 Iodine-125 SPECT 개발 을 위한 컴퓨터 시뮬레이션" 38 : 75-, 2004

3 정용현, "분자영상 획득을 위한 핵의학 영상기기" 대한핵의학회 38 (38): 131-139, 2004

4 Raghunathan P, "collimators for pixellated gamma camera" 07 : 104-, 2005

5 Weber DA, "Ultra-high-resolution imaging of small animals: Implications for preclinical and research studies" 6 : 332-344, 1999

6 Ogawa K, "Ultra high resolution pinhole SPECT for small animal study" 45 : 3122-3126, 1998

7 Strand SE, "Small animal imaging with pinhole single photon emission computed tomography" 73 : 981-984, 1994

8 Weber DA, "Pinhole SPECT: Ultra-high resolution imaging for small animal studies [Editorial]" 6 : 2287-2289, 1995

9 Weber DA, "Pinhole SPECT: An approach to in vivo high resolution SPECT imaging in small laboratory animals" 35 : 342-348, 1994

10 Song TY, "Optimization of pinhole collimator for small animal SPECT using Monte Carlo simulation" 50 : 327-332, 2003

11 Staelens S, "Monte Carlo simulations of a scintillation camera using GATE: validation and application modelling" 48 : 3021-3042, 2003

12 Jan S, "GATE: a simulation toolkit for PET and SPECT" 49 : 4543-4561, 2004

13 Hirai T, "Evaluation of myocardial infarct size in rat heart by pinhole SPECT" 7 : 107-111, 2000

14 Wu MC, "ECG-gated pinhole SPECT in mice with millimeter spatial resolution" 47 : 1218-1221, 2000

15 Bong JK, "Computer Simulation for Effects of Scintillator and Parallel Hole Collimator on Gamma Probe Imaging" 19 : 563-570, 1998

16 Schramm N, "Compact high resolution detector for small animal SPECT" 47 : 1163-1167, 2000