천연자원약물개발에 관한 연구 : 담쟁이덩굴이 흰쥐 신기능에 미치는 영향 Effect of Parthenocissus tricuspidata on rat kidney function = A study of Development of Natural Resources

다국어 초록 (Multilingual Abstract)

The Stem and the Radix of Parthenocissus tricuspidate (Vitaceae) have been used in arthrities laryngitis, jundice, neuralgia, renal insufficiency in folk remedies. In order to investigate the effects of their water extractums. on kidney function of normal and acute renal failure rats induced by the single s.c. injection of 2mg/kg HgCl_2, urinary volume, excretion rates of Na, K, Cl, serum chemical parameters were measured. The radix ex. 1.0g/kg showed significant diuretic action at 1-2hr. after administration. In renal failure group, the stem rather than the radix increase urin volume, electrolyte excretion at 2-5hr. after administration compared with 4-5hr. of furosemide and they didn't affect the level of serum parameters.