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    심장수술 환자의 섬망예측을 위한 PRE-Deliric 모델과 E-PRE-Deliric 모델의 타당도 비교 = Comparison of the Validity of the PRE-DELIRIC model and the E-PRE-DELIRIC model for Predicting Delirium in patients after Cardiac Surgery

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    https://www.riss.kr/link?id=A109220187

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    Purpose: The purpose of this study was to analyze the validity of the PRE-DELIRIC model and E-PRE-DELIRIC model. Methods: Patients who underwent cardiac surgery at a tertiary hospital between January 2019 and December 2022 were included. The presence or absence of delirium was determined based on risk groups, and the sensitivity, specificity, positive predictive power, and negative predictive power were verified using the Youden index. Receiver operating characteristic curves were derived for the PRE-DELIRIC model and E-PRE-DELIRIC model, the area under the curve was calculated, and the 95% confidence interval (CI) was presented. Results: The incidence of delirium was 28.8%. The average scores of the PRE-DELIRIC model and E-PRE-DELIRIC model were 49.72±29.91 and 18.14±0.41, respectively. In the PRE-DELIRIC model, for which a cut-off point of 14.05 was established using the Youden index, the sensitivity, specificity, positive predictive power, and negative predictive power were 64.8%, 83.2%, 61.0%, and 85.4%, respectively. In the E-PRE-DELIRIC model, with a cut-off point of 64.01, the corresponding indicators were 73.1%, 51.5%, 37.8%, and 82.6%, respectively. The areas under the curve for the PRE-DELIRIC model and the E-PRE-DELIRIC model were 0.77 (95% CI, 0.74-0.82) and 0.65 (95% CI, 0.61-0.69), respectively. Conclusion: It may be helpful to use both the E-PRE-DELIRIC and PRE-DELIRIC models. The two prediction models are expected to help improve the quality of nursing for the early detection and prevention of delirium, enabling intensive observations and interventions for patients at high risk of delirium.
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    Purpose: The purpose of this study was to analyze the validity of the PRE-DELIRIC model and E-PRE-DELIRIC model. Methods: Patients who underwent cardiac surgery at a tertiary hospital between January 2019 and December 2022 were included. The presence ...

    Purpose: The purpose of this study was to analyze the validity of the PRE-DELIRIC model and E-PRE-DELIRIC model. Methods: Patients who underwent cardiac surgery at a tertiary hospital between January 2019 and December 2022 were included. The presence or absence of delirium was determined based on risk groups, and the sensitivity, specificity, positive predictive power, and negative predictive power were verified using the Youden index. Receiver operating characteristic curves were derived for the PRE-DELIRIC model and E-PRE-DELIRIC model, the area under the curve was calculated, and the 95% confidence interval (CI) was presented. Results: The incidence of delirium was 28.8%. The average scores of the PRE-DELIRIC model and E-PRE-DELIRIC model were 49.72±29.91 and 18.14±0.41, respectively. In the PRE-DELIRIC model, for which a cut-off point of 14.05 was established using the Youden index, the sensitivity, specificity, positive predictive power, and negative predictive power were 64.8%, 83.2%, 61.0%, and 85.4%, respectively. In the E-PRE-DELIRIC model, with a cut-off point of 64.01, the corresponding indicators were 73.1%, 51.5%, 37.8%, and 82.6%, respectively. The areas under the curve for the PRE-DELIRIC model and the E-PRE-DELIRIC model were 0.77 (95% CI, 0.74-0.82) and 0.65 (95% CI, 0.61-0.69), respectively. Conclusion: It may be helpful to use both the E-PRE-DELIRIC and PRE-DELIRIC models. The two prediction models are expected to help improve the quality of nursing for the early detection and prevention of delirium, enabling intensive observations and interventions for patients at high risk of delirium.

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    참고문헌 (Reference)

    1 Gao W, "Validation of E-PRE-DELIRIC in cardiac surgical ICU Delirium : a retrospective cohort study" 27 (27): 233-239, 2022

    2 Paton L, "Utility of the PRE-DELIRIC delirium prediction model in a Scottish ICU cohort" 17 (17): 202-206, 2016

    3 Chen X, "Risk predictive models for delirium in the intensive care unit : a systematic review and meta-analysis" 10 (10): 1467-1480, 2021

    4 Lee A, "Risk prediction models for delirium in the intensive care unit after cardiac surgery : a systematic review and independent external validation" 118 (118): 391-399, 2017

    5 Chen H, "Risk factors of postoperative delirium after cardiac surgery : a meta-analysis" 16 (16): 113-, 2021

    6 김종란 ; 안정아, "Risk factors for delirium in trauma intensive care unit patients" 32 (32): 623-631, 2020

    7 Greaves D, "Risk factors for delirium and cognitive decline following coronary artery bypass grafting surgery : a systematic review and meta-analysis" 9 (9): e017275-, 2020

    8 Nahm Francis Sahngun, "Receiver operating characteristic curve : overview and practical use for clinicians" 75 (75): 25-36, 2022

    9 Van den Boogaard M, "Recalibration of the delirium prediction model for ICU patients(PRE-DELIRIC) : a multinational observational study" 40 (40): 361-369, 2014

    10 Zhang W, "Profiles of delirium and the clinical outcomes of patients who underwent coronary artery bypass grafting : a prospective study from China" 25 (25): 631-641, 2016

    1 Gao W, "Validation of E-PRE-DELIRIC in cardiac surgical ICU Delirium : a retrospective cohort study" 27 (27): 233-239, 2022

    2 Paton L, "Utility of the PRE-DELIRIC delirium prediction model in a Scottish ICU cohort" 17 (17): 202-206, 2016

    3 Chen X, "Risk predictive models for delirium in the intensive care unit : a systematic review and meta-analysis" 10 (10): 1467-1480, 2021

    4 Lee A, "Risk prediction models for delirium in the intensive care unit after cardiac surgery : a systematic review and independent external validation" 118 (118): 391-399, 2017

    5 Chen H, "Risk factors of postoperative delirium after cardiac surgery : a meta-analysis" 16 (16): 113-, 2021

    6 김종란 ; 안정아, "Risk factors for delirium in trauma intensive care unit patients" 32 (32): 623-631, 2020

    7 Greaves D, "Risk factors for delirium and cognitive decline following coronary artery bypass grafting surgery : a systematic review and meta-analysis" 9 (9): e017275-, 2020

    8 Nahm Francis Sahngun, "Receiver operating characteristic curve : overview and practical use for clinicians" 75 (75): 25-36, 2022

    9 Van den Boogaard M, "Recalibration of the delirium prediction model for ICU patients(PRE-DELIRIC) : a multinational observational study" 40 (40): 361-369, 2014

    10 Zhang W, "Profiles of delirium and the clinical outcomes of patients who underwent coronary artery bypass grafting : a prospective study from China" 25 (25): 631-641, 2016

    11 Czok M, "Postoperative neurocognitive disorders in cardiac surgery : investigating the role of intraoperative hypotension. A systematic review" 18 (18): 786-, 2021

    12 Leotsakos I, "Postoperative delirium after urological surgery : a literature review" 13 (13): 133-140, 2019

    13 Jin Z, "Postoperative delirium : perioperative assessment, risk reduction, and management" 125 (125): 492-504, 2020

    14 Lin L, "Outcomes of postoperative delirium in patients undergoing cardiac surgery : a systematic review and meta-analysis" 9 : 884144-, 2022

    15 Hamadnalla H, "Optimal interval and duration of CAM-ICU assessments for delirium detection after cardiac surgery" 71 : 110233-, 2021

    16 Dean AG, "OpenEpi: Open source epidemiologic statistics for public health, version 3.01"

    17 Wassenaar A, "Multinational development and validation of an early prediction model for delirium in ICU patients" 41 (41): 1048-1056, 2015

    18 Rohatgi N, "Initiative for prevention and early identification of delirium in medical-surgical units : lessons learned in the past five year" 132 (132): 1421-1430, 2019

    19 Mart MF, "ICU Survivorship-The relationship of delirium, sedation, dementia, and acquired weakness" 49 (49): 1227-1240, 2021

    20 Steenblock J, "Frailty index and its association with the onset of postoperative delirium in older adults undergoing elective surgery" 23 (23): 90-, 2023

    21 Chen KC, "Footprint analysis of flatfoot in preschool-aged children" 170 : 611-617, 2011

    22 Kim NY, "Factors related to delirium of intensive care unit patients in Korea : a systematic review" 50 (50): 1526-1535, 2021

    23 Kim SE, "External validation and comparison of two delirium prediction models in patients admitted to the cardiac intensive care unit" 9 : 947149-, 2022

    24 Ho MH, "Diagnostic test accuracy meta-analysis of PRE-DELIRIC(PREdiction of DELIRium in ICu patients) : a delirium prediction model in intensive care practice" 57 : 102784-, 2020

    25 남애리나 ; 박지원, "Development of korean intensive care delirium screening tool(KICDST)" 46 (46): 149-158, 2016

    26 Van den Boogaard M, "Development and validation of PRE-DELIRIC (PREdiction of DELIRium in ICu Patients)delirium prediction model for intensive care patients: observational multicentre Study" 344 : e420-, 2012

    27 MacLullich AMJ, "Delirium research, education and practice" 48 (48): 619-623, 2019

    28 Wassenaar A, "Delirium prediction in the intensive care unit : comparison of two delirium prediction models" 22 (22): 114-, 2018

    29 Kappen PR, "Delirium in neurosurgery : a systematic review and meta-analysis" 45 (45): 329-341, 2022

    30 Ely EW, "Delirium in mechanically ventilated patients validity and reliability of the confusion assessment method for the intensive care unit(CAM-ICU)" 286 (286): 2703-2710, 2001

    31 First MB, "DSM-5-TR : overview of what's new and what's changed" 21 (21): 218-219, 2022

    32 Kucuk O, "Comparison of the effectiveness of delirium evaluation tools in intensive care patients : pre-deliric versions 1 and 2, E-pre-deliric and ICDSC" 27 (27): 10365-10374, 2023

    33 Devlin JW, "Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU" 46 (46): e825-e873, 2018

    34 Heesakkers H, "Association between delirium prediction scores and days spent with delirium" 58 : 6-9, 2020

    35 Ewers R, "An exploration of the reliability and usability of two delirium screening tools in an Australian intensive care unit : a pilot study" 62 : 102919-, 2021

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