Background and Objectives : We compared the pain reducing effect of orally administered glucose with that of EMLA cream and pacifiers during venipuncture in preterm infants.
Material and Method : Twenty two preterm infants were included for this stu...
Background and Objectives : We compared the pain reducing effect of orally administered glucose with that of EMLA cream and pacifiers during venipuncture in preterm infants.
Material and Method : Twenty two preterm infants were included for this study. We performed four methods in al1 preterm infants. First, control group, second, received EMLA cream on the skin, third, received 30% glucose orally administered, and fourth, received pacifiers. Symptoms associated with pain at venipuncture were measured with the Premature Infants Pain Profile (PIPP) scale.
Result : Among the subjects, 14 (63.6%) was male, 8 (36.4%) was female. The distribution of gestational age was as follows ; gestational age 30~34 was 2, 32333 was 2, 34-35 was 10, 36-37 was 8. The comparison of PIPP score between groups was as follows : control group was 12.73±2.45, EMLA group was 10. 05±3.59, 30% glucose group was 6.45±2.06, pacifiers group was 9.18±2.32 (P<0.001). The percentage of patients with PIPP score above 12 was as follows : control group was 68.5%, EMLA group was 31.8%, 30% glucose group was 0%, pacifiers group was 14.5%. The mean heart rate change between before and after venipuncture was as follows : control group was 22.32±4.09, EMLA group was 31.91±3.53, 30% glucose group was 7.00±4.14, pacifiers group was 9.36±2.15.
Conclusion : Our study supports the use of oral glucose, EMLA, and pacifers is the effective intervention at venipuncture in preterm infants. The most effective method was oral glucose.