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      백반증을 동반한 아토피피부염 환자에서 Cyclosporine 투여 후 백반증이 호전된 증례 = Vitiligo Lesions Improved after Oral Cyclosporine in a Patient with Vitiligo and Atopic Dermatitis

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      https://www.riss.kr/link?id=A60003202

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      다국어 초록 (Multilingual Abstract)

      Vitiligo is an acquired cutaneous disorder of pigmentation with no definite etiology. Although there are a number of treatment modalities including phototherapy, topical corticosteroids and topical immunomodulators, few studies on the effect of systemic cyclosporine for the treatment of vitiligo have been conducted. We have experienced the improvement of vitiligo lesions after 8 months of systemic administration of cyclosporine (2.5~3.3 mg/kg/day) in a patient with vitiligo and atopic dermatitis. We believe this case report warrants further investigations of cyclosporine for the treatment of vitiligo in terms of mechanisms and clinical outcomes as well. (Korean J Dermatol 2012;50(2):159~162)
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      Vitiligo is an acquired cutaneous disorder of pigmentation with no definite etiology. Although there are a number of treatment modalities including phototherapy, topical corticosteroids and topical immunomodulators, few studies on the effect of system...

      Vitiligo is an acquired cutaneous disorder of pigmentation with no definite etiology. Although there are a number of treatment modalities including phototherapy, topical corticosteroids and topical immunomodulators, few studies on the effect of systemic cyclosporine for the treatment of vitiligo have been conducted. We have experienced the improvement of vitiligo lesions after 8 months of systemic administration of cyclosporine (2.5~3.3 mg/kg/day) in a patient with vitiligo and atopic dermatitis. We believe this case report warrants further investigations of cyclosporine for the treatment of vitiligo in terms of mechanisms and clinical outcomes as well. (Korean J Dermatol 2012;50(2):159~162)

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      참고문헌 (Reference)

      1 Tjioe M, "Topiccal macrolide immunomodulators: a role in the treatment of vitiligo?" 7 : 7-12, 2006

      2 Grimes PE, "Topical tacrolimus for repigmentation of vitiligo" 47 : 789-791, 2002

      3 Boone B, "Topical pimecrolimus in the treatment of vitiligo" 17 : 55-61, 2007

      4 Armor KT, "The use of cyclosporine in dermatology: Part I" 63 : 925-946, 2010

      5 Taieb A, "Tacrolimus and the pigmentary system" 210 : 177-178, 2005

      6 Smith DA, "Repigmentation of vitiligo with topical tacrolimus" 205 : 301-303, 2002

      7 Passeron T, "Physiopathology and genetics of vitiligo" 25 : 63-68, 2005

      8 Moretti S, "New insights into the pathogenesis of vitiligo: imbalance of epidermal cytokines at sites of lesions" 15 : 87-92, 2002

      9 Dell’Anna ML, "Mitochondrial impairment in peripheral blood mononuclear cells during the active phase of vitiligo" 117 : 908-913, 2001

      10 Wankowicz-Kalinska A, "Immunopolarization of CD4+ and CD8+ T cells to Type-1-like is associated with melanocyte loss in human vitiligo" 83 : 683-695, 2003

      1 Tjioe M, "Topiccal macrolide immunomodulators: a role in the treatment of vitiligo?" 7 : 7-12, 2006

      2 Grimes PE, "Topical tacrolimus for repigmentation of vitiligo" 47 : 789-791, 2002

      3 Boone B, "Topical pimecrolimus in the treatment of vitiligo" 17 : 55-61, 2007

      4 Armor KT, "The use of cyclosporine in dermatology: Part I" 63 : 925-946, 2010

      5 Taieb A, "Tacrolimus and the pigmentary system" 210 : 177-178, 2005

      6 Smith DA, "Repigmentation of vitiligo with topical tacrolimus" 205 : 301-303, 2002

      7 Passeron T, "Physiopathology and genetics of vitiligo" 25 : 63-68, 2005

      8 Moretti S, "New insights into the pathogenesis of vitiligo: imbalance of epidermal cytokines at sites of lesions" 15 : 87-92, 2002

      9 Dell’Anna ML, "Mitochondrial impairment in peripheral blood mononuclear cells during the active phase of vitiligo" 117 : 908-913, 2001

      10 Wankowicz-Kalinska A, "Immunopolarization of CD4+ and CD8+ T cells to Type-1-like is associated with melanocyte loss in human vitiligo" 83 : 683-695, 2003

      11 Brady AJ, "Hyperpigmentation due to cyclosporine therapy" 4 : 309-310, 1989

      12 Lan CC, "FK506 promotes melanocyte and melanoblast growth and creates a favourable milieu for cell migration via keratinocytes: possible mechanisms of how tacrolimus ointment induces repigmentation in patients with vitiligo" 153 : 498-505, 2005

      13 Lan CC, "FK506 (tacrolimus) and endothelin combined treatment induces mobility of melanoblasts: new insights into follicular vitiligorepigmentation induced by topical tacrolimus on sun-exposed skin" 164 : 490-496, 2011

      14 Szepietowski J, "Excess benign melanocytic naevi in renal transplant recipients" 194 : 17-19, 1997

      15 Lee JY, "Effect of cyclosporine A on melanogenesis in cultured human melanocytes" 16 : 504-508, 2003

      16 Young-Sook Lee, "Downregulation of NFAT2 promotes melanogenesis in B16 melanoma cells" 대한해부학회 43 (43): 303-309, 2011

      17 Rebora A, "Cyclosporin A-induced hair darkening" 38 : 229-230, 1999

      18 Ozkaya-Bayazit E, "Bullous acral erythema and concomitant pigmentation on the face and occluded skin" 14 : 139-140, 2000

      19 Stinco G, "An open randomized study to compare narrow band UVB, topical pimecrolimus and topical tacrolimus in the treatment of vitiligo" 19 : 588-593, 2009

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-06-29 학술지명변경 외국어명 : 미등록 -> Korean Journal of Dermatology KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.11 0.11 0.13
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.13 0.14 0.254 0.01
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