악성화및 간전이를 동반한 Peutz-Jeghers 증후군 = A Case of Peutz-Jeghers Syndrome with Malignant Change and Hepatic Metastasis

다국어 초록 (Multilingual Abstract)

The Peutz-Jeghers syndrome, characterized by pigmentation of the skin and mucous membranes and gastrointestinal polyposis of harmatomatous variety, has been well docu- mented, there have been conflicting view, however, as to frequency with which malignant change occurs in the polyp. There are insufficient data to establish this syndrome as a precancerous condition but documented cases of gastrointestinal cancer arising in this syndrome have been reported with an incidence of 2 3%. This report is concerned with our experience with a case of Peutz Jeghers syndrome with adenocarcinoma as arising in colonic polyps, which metastasized to omentum and regional lymph nodes and liver. Histologically the polyps were mostly harmatomatous and one was transformed into adenocarcinoma and liver showsed adenocarcinoma in the metastatic sites.(Korea J Gastro- enterol 1994;26:363-368)