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      향정신성 약물투여가 정상수면에 미치는 영향  :  Amitriptyline을 중심으로 = The Effects of Psychotropic Drug on Normal Sleep

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      https://www.riss.kr/link?id=A19594893

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      To identify the effects of psychotropic drug on normal sleep structure, author administrated 25mg of amitriptyline to 6 healthy young adults aged from 20 to 24, and applied polysomnography for analizing sleep structure.
      The results were summarized as follows.
      1. In normal adults, there were great individual variations in the ditribution of relative value (%) of sleep structure.
      2. Compaired with the baseline, total sleep time increased significantly in the 25mg amitriptyline night, and REM latency shortened significantly in the first and second recovery night.
      3. Compaired with the baseline, the relative value (%) of each sleep stage to total sleep time was as follows.
      1) Stage 1 sleep decreased significantly in the first recovery night.
      2) Stage 2 sleep increased significantly in the amitriptyline night.
      3) Slow wave sleep decreased significantly in the first recovery night.
      4) REM sleep decreased significantly in the amitriptyline night, and increased significantly in the first and second recovery nights.
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      To identify the effects of psychotropic drug on normal sleep structure, author administrated 25mg of amitriptyline to 6 healthy young adults aged from 20 to 24, and applied polysomnography for analizing sleep structure. The results were summarized as...

      To identify the effects of psychotropic drug on normal sleep structure, author administrated 25mg of amitriptyline to 6 healthy young adults aged from 20 to 24, and applied polysomnography for analizing sleep structure.
      The results were summarized as follows.
      1. In normal adults, there were great individual variations in the ditribution of relative value (%) of sleep structure.
      2. Compaired with the baseline, total sleep time increased significantly in the 25mg amitriptyline night, and REM latency shortened significantly in the first and second recovery night.
      3. Compaired with the baseline, the relative value (%) of each sleep stage to total sleep time was as follows.
      1) Stage 1 sleep decreased significantly in the first recovery night.
      2) Stage 2 sleep increased significantly in the amitriptyline night.
      3) Slow wave sleep decreased significantly in the first recovery night.
      4) REM sleep decreased significantly in the amitriptyline night, and increased significantly in the first and second recovery nights.

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