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      KCI등재 SCI SCIE SCOPUS

      A Case of Ischemic Colitis Associated with the Herbal Food Supplement Ma Huang

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      https://www.riss.kr/link?id=A101616682

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      다국어 초록 (Multilingual Abstract)

      Ischemic colitis is a condition that usually occurs in the elderly, as a form of vascular disease. However, ischemic colitis also occurs, though rarely, in healthy young adults. Moreover, food supplements containing Ephedra sinica or ma huang have been linked to adverse central nervous and cardiovascular events. A 40-year-old man was admitted to our emergency department after 2 episodes of abdominal pain and bloody diarrhea that lasted 24 hours. His medical history was unremarkable for risk factors of bowel ischemia, except for well-controlled hypertension. However, a weight-loss supplement, Ephedra sinica, had been prescribed for daily use during the previous month. Both abdominal/pelvic computed tomography and colonoscopy revealed findings compatible with ischemic colitis. His conditions spontaneously improved without any serious complications, and he was advised to discontinue the use of herbal medications containing ephedrine. In this paper, we describe a case of ischemic colitis that was potentially linked to the use of ma huang with a review of the relevant literature.
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      Ischemic colitis is a condition that usually occurs in the elderly, as a form of vascular disease. However, ischemic colitis also occurs, though rarely, in healthy young adults. Moreover, food supplements containing Ephedra sinica or ma huang have bee...

      Ischemic colitis is a condition that usually occurs in the elderly, as a form of vascular disease. However, ischemic colitis also occurs, though rarely, in healthy young adults. Moreover, food supplements containing Ephedra sinica or ma huang have been linked to adverse central nervous and cardiovascular events. A 40-year-old man was admitted to our emergency department after 2 episodes of abdominal pain and bloody diarrhea that lasted 24 hours. His medical history was unremarkable for risk factors of bowel ischemia, except for well-controlled hypertension. However, a weight-loss supplement, Ephedra sinica, had been prescribed for daily use during the previous month. Both abdominal/pelvic computed tomography and colonoscopy revealed findings compatible with ischemic colitis. His conditions spontaneously improved without any serious complications, and he was advised to discontinue the use of herbal medications containing ephedrine. In this paper, we describe a case of ischemic colitis that was potentially linked to the use of ma huang with a review of the relevant literature.

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      참고문헌 (Reference)

      1 Haller CA, "Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use" 71 : 421-432, 2002

      2 Ephedra, "Natural medicines comprehensive database" Therapeutic Research Faculty 400-403, 2000

      3 Rezkalla SH, "Myocardial infarction temporally related to ephedra-a possible role for the coronary microcirculation" 101 : 64-66, 2002

      4 Chen C, "Ischemic stroke after using over the counter products containing ephedra" 217 : 55-60, 2004

      5 Dowd J, "Ischemic colitis associated with pseudoephedrine: four cases" 94 : 2430-2434, 1999

      6 Ryan CK, "Ischemic colitis associated with herbal product use in a young woman" 15 : 309-312, 2002

      7 Lichtenstein GR, "Ischemic colitis associated with decongestant use" 132 : 682-, 2000

      8 Comay D, "Ischemic colitis after weight-loss medication" 17 : 719-721, 2003

      9 MacDonald PH, "Ischaemic colitis" 16 : 51-61, 2002

      10 Naik SD, "Ephedra-associated cardiomyopathy" 38 : 400-403, 2004

      1 Haller CA, "Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement use" 71 : 421-432, 2002

      2 Ephedra, "Natural medicines comprehensive database" Therapeutic Research Faculty 400-403, 2000

      3 Rezkalla SH, "Myocardial infarction temporally related to ephedra-a possible role for the coronary microcirculation" 101 : 64-66, 2002

      4 Chen C, "Ischemic stroke after using over the counter products containing ephedra" 217 : 55-60, 2004

      5 Dowd J, "Ischemic colitis associated with pseudoephedrine: four cases" 94 : 2430-2434, 1999

      6 Ryan CK, "Ischemic colitis associated with herbal product use in a young woman" 15 : 309-312, 2002

      7 Lichtenstein GR, "Ischemic colitis associated with decongestant use" 132 : 682-, 2000

      8 Comay D, "Ischemic colitis after weight-loss medication" 17 : 719-721, 2003

      9 MacDonald PH, "Ischaemic colitis" 16 : 51-61, 2002

      10 Naik SD, "Ephedra-associated cardiomyopathy" 38 : 400-403, 2004

      11 Charatan F, "Ephedra supplement may have contributed to sportsman's death" 326 : 464-, 2003

      12 McBride BF, "Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial" 291 : 216-221, 2004

      13 Shekelle PG, "Efficacy and safety of ephedra and ephedrine for weight loss and athletic performance: a meta-analysis" 289 : 1537-1545, 2003

      14 Sreenarasimhaiah J, "Diagnosis and management of intestinal ischaemic disorders" 326 : 1372-1376, 2003

      15 Krome CN, "Cardiac arrhythmia in a professional football player: Was ephedrine to blame?" 31 : 21-25, 2003

      16 Kalman D, "An acute clinical trial evaluating the cardiovascular effects of an herbal ephedra-caffeine weight loss product in healthy overweight adults" 26 : 1363-1366, 2002

      17 Pittler MH, "Adverse events of herbal food supplements for body weight reduction: systematic review" 6 : 93-111, 2005

      18 Haller CA, "Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids" 343 : 1833-1838, 2000

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
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      2002-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 1.42 0.3 0.99
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.83 0.72 0.546 0.08
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