화재에 의한 흡입연기의 호흡기 내 침착에 관한 연구 = Deposition of Inhaled Smoke Particles Produced by Fire

국문 초록 (Abstract)

호흡기 내에서 유해물질의 체내흡수 및 방어특성은 영역별로 다르며 흡입연기의 장·단기 인체 유해성 은 연기의 호흡기 내 침착위치 및 침착밀도와 밀접한 관계를 가지고 있다. 이 연구에서는 미소부피 위치 추적법을 이용한 입자침착율 계산 기법을 사용하여 휴식 및 가벼운 운동에 해당하는 호흡조건별로 또한 구강 및 비강 호흡별로 각 입자크기에 대하여 호흡기 각 영역별로 단위 면적당 침착분율 등 침착 특성을 구하였다. 이 결과는 연기에 흡착된 유해물질의 체내 흡수량 산정 등에 이용되어 연기의 인체 유해성 판 정에 도움을 줄 수 있을 것으로 판단된다.

다국어 초록 (Multilingual Abstract)

The absorption characteristics of hazardous materials onto human body and defense mechanism differ from each other region within the respiratory tracts, thus adverse health effects of inhaled smokes are associated with not only the concentration but also the location of the particles deposited. In this work, the deposition fraction per surface area and the deposition sites of the smoke particles in human respiratory tracts for each rest and light exercise conditions together with oral and nasal breathing were calculated by using segmental volume tracking method. The results would be used for deriving the amount of absorption of hazardous materials onto human body, thus contribute to the health risk assessments of inhaled fire smokes.

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