RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      KCI등재 SCOPUS

      중년 여성의 렙틴 수용체 유전자 다형성과 신체구성상 특성의 관련성 = Relationship between Gln223Arg polymorphism in the leptin receptor gene and body composition in middle-aged women

      한글로보기

      https://www.riss.kr/link?id=A40132409

      • 0

        상세조회
      • 0

        다운로드
      서지정보 열기
      • 내보내기
      • 내책장담기
      • 공유하기
      • 오류접수

      부가정보

      다국어 초록 (Multilingual Abstract)

      Kim, K.J., Ahn, N.Y., Cheon, W.K., Park, J.S., Hong, C.B., Shin, Y.J., Kim. S.H., Kim, T.H., Lee, J.E. Relationship between Gln223Arg polymorphism in the leptin receptor gene and body composition in middle-aged women. Exercise Science, 13(2): 233-240, 2004. Previous studies have been found for the polymorphism in the leptin receptor gene being involved in human obesity, We examined relationship between the Gln223Arg polymorphism in the leptin receptor gene and body composition. Subjects were consisted of obese group (N=94) and normal weight group (N=95) in middle-aged women. Body weight, %fat, BMI, skinfold thickness, body circumferences, and WHR we measured for the analysis of the detailed physique. Leptin receptor polymorphism was detected by PCR-RELP assays. The Gln223Arg polymorphism in the leptin receptor gene was no significant difference between obese and normal weight group, and heterozygous for the leptin receptor gene showed the highest values in both groups. The allele frequency was no significant difference between obese and normal weieht group. Body weight and BMI showed a significant (p<0.05) difference between mutant homozygous and heterozygous of the Gln223Arg in the leptin receptor gene in both groups. Hip and high circumferences showed a significant (p<0.05) difference between mutant homozygous and heterozygous of Gln223Arg in the leptin receptor gene in both groups. Although it was no significance, skinfold thickness of mutant homozygous group showed a high values than mutant heterozygous group in obese group. Therefore the Gln223Arg polymorphism of the leptin gene receptor not appeared to be a risk factor for obesity in middle-aged Korean women, but we suggest that the Gln223Arg polymorphism of the leptin gene receptor affect to the body composition.
      번역하기

      Kim, K.J., Ahn, N.Y., Cheon, W.K., Park, J.S., Hong, C.B., Shin, Y.J., Kim. S.H., Kim, T.H., Lee, J.E. Relationship between Gln223Arg polymorphism in the leptin receptor gene and body composition in middle-aged women. Exercise Science, 13(2): 233-240,...

      Kim, K.J., Ahn, N.Y., Cheon, W.K., Park, J.S., Hong, C.B., Shin, Y.J., Kim. S.H., Kim, T.H., Lee, J.E. Relationship between Gln223Arg polymorphism in the leptin receptor gene and body composition in middle-aged women. Exercise Science, 13(2): 233-240, 2004. Previous studies have been found for the polymorphism in the leptin receptor gene being involved in human obesity, We examined relationship between the Gln223Arg polymorphism in the leptin receptor gene and body composition. Subjects were consisted of obese group (N=94) and normal weight group (N=95) in middle-aged women. Body weight, %fat, BMI, skinfold thickness, body circumferences, and WHR we measured for the analysis of the detailed physique. Leptin receptor polymorphism was detected by PCR-RELP assays. The Gln223Arg polymorphism in the leptin receptor gene was no significant difference between obese and normal weight group, and heterozygous for the leptin receptor gene showed the highest values in both groups. The allele frequency was no significant difference between obese and normal weieht group. Body weight and BMI showed a significant (p<0.05) difference between mutant homozygous and heterozygous of the Gln223Arg in the leptin receptor gene in both groups. Hip and high circumferences showed a significant (p<0.05) difference between mutant homozygous and heterozygous of Gln223Arg in the leptin receptor gene in both groups. Although it was no significance, skinfold thickness of mutant homozygous group showed a high values than mutant heterozygous group in obese group. Therefore the Gln223Arg polymorphism of the leptin gene receptor not appeared to be a risk factor for obesity in middle-aged Korean women, but we suggest that the Gln223Arg polymorphism of the leptin gene receptor affect to the body composition.

      더보기

      참고문헌 (Reference)

      1 "한국인에서 렙틴수용체 유전자 다형성과 체지방 분포" 10 (10): 182-189, 2001182-189

      2 "The hypothalamic leptin receptor in humans identification of incidental sequence poly- morphism and absence of the db/db mouse and fa/fa rat mutations" 45 : 992-994, 1996

      3 "The Gln223Arg and Lys656Asn polymorphism in the human leptin receptor do not associate with traits related to obesity" Diabetes 46 : 1898-1900, 19971898-1900

      4 "Strueture and sequence variation at the human leptin receptor gene in lean and obese Pima Indians" Genet 6 : 675-679, 1997

      5 "Positional cloning of the mouse obese gene and its human homologue" 425-432, 1994

      6 "Polymorphism in the leptin receptor gene body composition and fat distribution in overweight and obese women" 25 (25): 714-720, 2001

      7 "Phenotypes of mouse diabetes and rat fatty due to mutations in the OB" Science 994-6, 1996

      8 "Leptin receptor gene variation obesity:lack of association in a white British male population" Genet 6 : 869-76, 1997

      9 "Leptin and the regulation of body weight in mammals" 395 : 763-770, 1998

      10 "Identification of SOCS-3 as a potential mediator of central leptin resistance" 619-625, 1998

      1 "한국인에서 렙틴수용체 유전자 다형성과 체지방 분포" 10 (10): 182-189, 2001182-189

      2 "The hypothalamic leptin receptor in humans identification of incidental sequence poly- morphism and absence of the db/db mouse and fa/fa rat mutations" 45 : 992-994, 1996

      3 "The Gln223Arg and Lys656Asn polymorphism in the human leptin receptor do not associate with traits related to obesity" Diabetes 46 : 1898-1900, 19971898-1900

      4 "Strueture and sequence variation at the human leptin receptor gene in lean and obese Pima Indians" Genet 6 : 675-679, 1997

      5 "Positional cloning of the mouse obese gene and its human homologue" 425-432, 1994

      6 "Polymorphism in the leptin receptor gene body composition and fat distribution in overweight and obese women" 25 (25): 714-720, 2001

      7 "Phenotypes of mouse diabetes and rat fatty due to mutations in the OB" Science 994-6, 1996

      8 "Leptin receptor gene variation obesity:lack of association in a white British male population" Genet 6 : 869-76, 1997

      9 "Leptin and the regulation of body weight in mammals" 395 : 763-770, 1998

      10 "Identification of SOCS-3 as a potential mediator of central leptin resistance" 619-625, 1998

      11 "Human leptin receptors gene in obese Japanese subjects evidence against either obesity-causing mutations or association of sequence variants with obesity" Diabe- tologia 40 : 1204-1210, 1997

      12 "Congenital leptin deficiency is associated with severe early-onset obesity in humans" 387 : 903-908, 1997

      13 "Central nervous system control of food intake" 404 (404): 661-671, 2000

      14 "Association of Trp64Arg polymorphism of the beta3-adrenergic receptor gene and no association of Gln223Arg polymorphism of the leptin receptor gene in japanese schoolchildren with obesity" 24 : 443-449, 2000

      15 "Associ- ations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study" 85 : 29-34, 2000

      16 "Abnormal splicing of the leptin receptor in diabetic mice" Nature 379 : 632-635, 1996

      17 "A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction" 392 : 398-401, 1998

      더보기

      분석정보

      View

      상세정보조회

      0

      Usage

      원문다운로드

      0

      대출신청

      0

      복사신청

      0

      EDDS신청

      0

      동일 주제 내 활용도 TOP

      더보기

      주제

      연도별 연구동향

      연도별 활용동향

      연관논문

      연구자 네트워크맵

      공동연구자 (7)

      유사연구자 (20) 활용도상위20명

      인용정보 인용지수 설명보기

      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-03-21 학회명변경 한글명 : 한국운동과학회 -> 한국운동생리학회
      영문명 : Korea Exercise Science Academy -> Korean Society of Exercise Physiology
      KCI등재
      2005-03-21 학회명변경 한글명 : 한국운동과학회 -> 한국운동생리학회
      영문명 : Korea Exercise Science Academy -> Korean Society of Exercise Physiology
      KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2001-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      더보기

      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.76 0.76 0.67
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.62 0.71 0.674 0.03
      더보기

      이 자료와 함께 이용한 RISS 자료

      나만을 위한 추천자료

      해외이동버튼