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DNA repair : methods and protocols

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https://www.riss.kr/link?id=M15351810

저자

Balakrishnan, Lata ; Stewart, Jason A
발행사항
New York, NY : Humana Press : Springer, c2019
발행연도
2019
작성언어
영어
주제어

Human genetics
DDC
611.01816 판사항(23)
ISBN
9781493995004
1493995006
자료형태
단행본(다권본)
발행국(도시)
New York(State)
서명/저자사항
DNA repair : methods and protocols / edited by Lata Balakrishnan, Jason A. Stewart.
형태사항
xv, 352 p. : ill. (some col.) ; 27 cm.
총서사항
Springer protocols Methods in Molecular Biology, 1064-3745 ; 1999 Springer protocols. Methods in molecular biology ; 1999.
일반주기명
Includes bibliographical references and index.
Homologous Recombination-Mediated DNA Repair and Implications for Clinical Treatment of Repair Defective Cancers -- Resolving Roadblocks to Telomere Replication -- In Time and Space: Laser Micro-Irradiation and the DNA Damage Response -- Quantification of Double Strand Breaks in Mammalian Cells using Pulsed-Field Electrophoresis -- Methods to Study Trinucleotide Repeat Instability Induced by DNA Damage and Repair -- Extracting and Measuring dNTP Pools in Saccharomyces cerevisiae -- Conversion Tract Analysis of Homology-Directed Genome Editing using Oligonucleotide Donors -- Reporter Assays for BER Pathways -- Methods for Studying DNA Single-Strand Break Repair and Signaling in Xenopus laevis Egg Extracts -- Chromatin Immunoprecipitation (ChIP) of Plasmid-Bound Proteins in Xenopus Egg Extracts -- Cellular Assays to Study the Functional Importance of Human DNA Repair Helicases -- A Mammalian Genetic Complementation Assay for Assessing Cellular Resistance to Genotoxic Compounds -- Small Molecule Inhibitor Screen for DNA Repair Proteins -- Assembling the Human Resectosome on DNA Curtains -- Thin-Layer Chromatography and Real-Time Coupled Assays to Measure ATP Hydrolysis -- Gel-Based Assays for Measuring DNA Unwinding, Annealing, and Strand Exchange -- In Vitro Assay for Plasmid Length DNA Strand Exchange by Human DMC1 -- In Vitro Assays for DNA Branch Migration -- Stabilization of Human DMC1 Nucleoprotein Filament -- Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA -- Single-Molecule DNA Fiber Analyses to Characterize Replication Fork Dynamics in Living Cells -- Direct Visualization of DNA Replication at Telomeres using DNA Fiber Combing Combined with Telomere FISH -- Telomere and G-Quadruplex Co-Localization Analysis by Immunofluorescence-Fluorescence In Situ Hybridization (IF-FISH) -- FISHing for Damage on Metaphase Chromosomes.
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