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      Graves` disease 에서의 자가임파구 혼합배양 반응 = Autologous Mixed Lymphocyte Culture Reaction ( AMLCR ) in Graves` Disease

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      https://www.riss.kr/link?id=A3305406

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      To study the hypothesis that impaired generation of suppressor T cell may play a role in the pathogenesis of Graves disease, autologous mixed lymphocyte culture which has been known to reflect the generation of suppressor T cell was done in 23 patients with Graves` disease. 1) In the AMLCR of Graves' disease, the mean stimulation index(5.2±3.8) was not significantly different from that of normal control(5.6±4.1), 2) The stimulation index did not correlate with the titer of antithyroglobulin antibody and the concentrations of thyroid hormones in Graves' disease. These results indicated that the generation of suppressor T cell is not impaired in the patients with Graves' disease, and which suggested that a defect in suppressor T cell generation does not contribute to the patbogenesis of the disease
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      To study the hypothesis that impaired generation of suppressor T cell may play a role in the pathogenesis of Graves disease, autologous mixed lymphocyte culture which has been known to reflect the generation of suppressor T cell was done in 23 patient...

      To study the hypothesis that impaired generation of suppressor T cell may play a role in the pathogenesis of Graves disease, autologous mixed lymphocyte culture which has been known to reflect the generation of suppressor T cell was done in 23 patients with Graves` disease. 1) In the AMLCR of Graves' disease, the mean stimulation index(5.2±3.8) was not significantly different from that of normal control(5.6±4.1), 2) The stimulation index did not correlate with the titer of antithyroglobulin antibody and the concentrations of thyroid hormones in Graves' disease. These results indicated that the generation of suppressor T cell is not impaired in the patients with Graves' disease, and which suggested that a defect in suppressor T cell generation does not contribute to the patbogenesis of the disease

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