쇠뜨기와 화살나무의 항암 효능에 관한 연구 = Studies on the Effects of Seddugi and Hwasalnamoo on the Anti-Cancer in Mice

다국어 초록 (Multilingual Abstract)

This study was designed to find out the anti-cancer effects of two herbs using a folk remedy in Korea-The two herbs were A: Equisetum arvense L. (Seddugi), B: Eunymus alatus Siebold. (Hwasalnamoo). The experiment for the anti-cancer effects were conducted in mice and experimental groups were divided into normal (NO), standard (ST) and two other(A, B) groups for each herb and each of the two experimental groups consisted of three sub-groups(Ⅰ, Ⅱ, Ⅲ) according to three different quantity doses of a folk remedy using five times and ten times the quantity of a commonly used in a folk remedy. The water soluble extracts of two herbs were orally administered to mice during six weeks followed by inoculation of the sarcoma-180 tumor cells into the peritoneal cavity. During experimental periods, the contents of ascites, abdominal circumference, and survival time were observed and the degree of invasiveness to the abdominal organs were observed histopathologically. The results of effects on anti-cancer were as follows: 1. The survival time was significantly prolonged by the two herbs, especially in groups AⅡ＆BⅡ. 2. Body weight, circumference of the abdomen and contents of ascites at the time of sacrifice were noted and significantly decreased in groups AⅠ, AⅡ＆BⅡ. 3. Anti-cancer effects evaluated by the invasiveness and thickness of the tumor cells were noted in groups AⅢ＆BⅡ.