허혈성 저처치가 일시적 저항성 운동 후 동맥경직도에 미치는 영향 = Remote Ischemic Preconditioning Does Not Attenuate Arterial Stiffening Following Acute High-Intensity Resistance Exercise

다국어 초록 (Multilingual Abstract)

Purpose: Whether remote ischemic preconditioning (RIPC), repeated bouts of ischemia and reperfusion, prevents arterial stiffening following an acute high-intensity resistance exercise (RE) is unknown. We tested the hypothesis that RIPC would attenuate arterial stiffening following acute high-intensity RE in healthy adults.
Methods: Using a randomized, single-blind, sham-controlled, crossover design, 14 adults (eight males and six females; age, 26±1 years) completed two testing sessions, separated by 1 week. Sessions consisted of either an RIPC intervention (4×5 minutes, 220 mm Hg, bilateral arm occlusion) or a sham condition (4×5 minutes, 20 mm Hg, bilateral arm occlusion) prior to RE (two sets, eight exercises, 80% of one repetition maximum). Carotid-femoral pulse wave velocity (cfPWV) and augmentation index at 75 beats per minute (AIx@75bpm) as indices of arterial stiffness and blood pressures were measured at baseline, immediately after RE, and 30 minutes, 1 hour after RE using an applanation tonometry.
Results: Brachial and central systolic blood pressures and cfPWV increased from baseline (p＜0.05), with no trial differences. No differences were observed for heart rate, brachial and central diastolic blood pressures, and AIx@75bpm.
Conclusion: These findings demonstrate that acute RE increased arterial stiffness, but this increase was not attenuated by RIPC when applied before RE. This suggests that RIPC prior to an acute bout of high-intensity RE may not protect against RE-induced arterial stiffening.