패혈증이 동반된 아토피피부염 치험 1례 = A Case of Atopic Dermatitis with Sepsis

다국어 초록 (Multilingual Abstract)

Objective : It is well known that patients with atopic dermatitis are prone to cutaneous infections. Especially Staphylococcus aureus has been regarded as having an influence on atopic dermatitis. We observed and treated a case of an adult atopic dermatitis patient with sepsis by cooperation of east-west medicine. We present this case because there were no former reports of atopic dermatitis with sepsis treated by cooperation of east-west medicine. Method : We used herbal medication, acupuncture, herbal wet dressing combined with antibiotics and analgesics for 19 days. Atopic dermatitis grade was determined using SCORAD index. Result : The SCORAD index was lowered 32.3 at discharge than before of which the SCORAD index was 62.5 at admission. Other systemic inflammatory response such as fever, pus was also resolved. Conclusion : From this result, we suggest that herbal therapy associated with antibiotic therapy were shown to treat atopic dermatitis with secondary infection effectively.

참고문헌 (Reference)

1 대한피부과학회 교과서 편찬위원회, "피부과학 개정4판" 여문각 164-, 2001

2 김영호, "표재성 황색포도구균의 존재와 그 외독소가 소아 아토피피부염에 미치는 영향" 대한 소아알레르기 호흡기학회 16 (16): 162-170, 2006

3 김재열, "패혈증" 대한결핵및호흡기학회 63 (63): 13-16, 2007

4 김문범, "아토피피부염에서의 피부관리" 대한피부과학회 47 (47): 531-538, 2009

5 유광호, "아토피피부염 환자에서의 표재성 진균증" 대한피부과학회 47 (47): 1-5, 2009

6 김정희, "아토피피부염 최신지견" 14 (14): 12-23, 2004

7 김영선, "소아 아토피피부염 환부에서의 이차 세균 감염 빈도와 항생제 감수성에 대한 연구" 대한 소아알레르기 호흡기학회 16 (16): 26-37, 2006

8 Leyden JJ, "Staphylococcus aureus in the lesions of atopic dermatitis" 90 : 525-530, 1974

9 Nishijima S, "Staphylococcus aureus in the anterior nares and subungual spaces of the hands in atopic dermatitis" 25 : 155-158, 1997

10 Hanifin JM, "Staphylococcal infections in patients with atopic dermatitis" 113 : 1383-1386, 1977

11 Leung DYM, "Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis, evidence for a new group of allergens" 92 : 1374-1380, 1993

12 Bunilowski R, "Evidence for a disease-promoting effect of Staphylococcus arueus-derived exotoxins in atopic dermatitis" 105 : 814-819, 2000

13 Tofte SJ, "Current management and therapy of atopic dermatitis" 44 : 13-16, 2001

14 Stevens SR, "Atopic dermatitis :current trends and future directions" 28 : 51-57, 2000