간질환자 두피뇌파의 발작사이간질모양방전과 배경파 델타영역: 전류원분포의 해부학적 연관성 = Interictal Epileptiform Discharges and Background Delta Frequency Bands in Scalp EEGs of Epileptic Patients: Anatomical Correlation between the Current Source Distributions

다국어 초록 (Multilingual Abstract)

Background: The intermittent delta activity in electroencephalographies (EEGs) of patients with focal brain lesions has been
reported to be a marker of an epileptogenic focus. This study investigated the concordance between the current source distribution
(CSD) of the interictal epileptiform discharges (IEDs) and that of the background delta frequency bands (DFBs)
of the scalp EEG. Methods: We collected scalp EEGs of 13 patients with focal epilepsy that contained uniregional IEDs
and unilateral delta to theta slow waves. We applied a distributed source model using LORETA® to determine the CSD of
the peak points of the IEDs and the DFBs of the background activity. Results: The CSDs of the DFBs were ipsilateral to
the CSDs of the peak point of the averaged IEDs in ten patients, and bilateral with ipsilateral predominance in three patients.
In the cases with an ipsilateral CSD of the DFB, 8 of 10 patients had concordance of the CSD localization between the
averaged IED and the DFB. In the cases with bilateral CSD of the DFB, 2 of 3 patients had concordance of the CSD localization
between the averaged IED and the DFB. Conclusions: The CSD localization and lateralization appear to be concordant
between the IEDs and the DFB of background activity in epileptic patients. Therefore, the CSD of the DFB in EEGs
with visually observable slow activities may predict those of IEDs.

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