Steroid receptors have been sugessted to play an important role in the synthesis of DNA and the growth of cells. Authors have estimated the concentrations of estrogen and progesteron receptors using the ELISA method, and the proliferative potential us...
Steroid receptors have been sugessted to play an important role in the synthesis of DNA and the growth of cells. Authors have estimated the concentrations of estrogen and progesteron receptors using the ELISA method, and the proliferative potential using immunohistochemical stain with the monoclonal antibody to bromodeoxyuridine(BUdR) in 46 human brain tumors(21 meningiomas, 12 astrocytomas, 7 schwannoma. 4 medullobastomas, and 2 pituitary tumors). In our studies, the concentration of receptors had no relationship with age and sex of patients, and tumor type, and the proliferative potential of the individual tumors.