Recent advances in wound healing using recombinant human epidermal growth factor = Recent advances in wound healing using recombinant human epidermal growth factor

다국어 초록 (Multilingual Abstract)

Wound healing is an interactive, dynamic, and continuous process involving inflammation, proliferation or tissue regeneration, and tissue remodeling. The role of epidermal growth factor (EGF) has been extensively investigated in wound healing. EGF plays a role as a direct mitogen for endothelial cells and dermal fibroblasts, which in turn accelerate re-epithelization and increase proliferation and tensile strength of the dermis. Topical application of EGF is well tolerated by most patients, and the drug is able to bypass the primary metabolism or digestion via the gastrointestinal tract, avoiding unwanted potential systemic effects. Nowadays, EGF has been widely administered to enhance the healing process in various kinds of wounds such as diabetic ulcer. In this session, we will discuss the efficacy and safety of recently developed topical EGF treatment by introducing some of our research data and a clinical case.