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      피부 비만세포증 30 예의 임상 및 병리 조직학적 고찰 = Clinicopathological study of 30 Cases of Cutaneous Mastocytosis피부 비만세포증 30 예의 임상 및 병리 조직학적 고찰

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      https://www.riss.kr/link?id=A19623531

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      다국어 초록 (Multilingual Abstract)

      Background : Mastoeytosis is characterized by accumulation of mast cells in various organs, most frequently in skin. Cutaneous mastoeytosis is a relatively rare disease in outpatient clinics and the clinicopathological study has not been done yet in Korea. Objective : The ain of this study is to analyse the clinieopathological features of cutaneous mastocytosis. In addition, we examined CDU7 expression in the skin biopsy specimens immunohistochemically Methods : Thirty cases of cutaneous mastocytosis were collected from 1990 to 1999 in Asan Medical Center. Clinical records, photographs. and biopsy slides were reviewed. In each biopsy specimen, CDU7 was stained by immunoperoxidase method. Results : Among 30 cases, 29 cases were childhood type urticaria pigmeniosa(76.7 %) or mastocytoma(20.2%) and only I case occurred after 16 years of age. The incidence showed a peak under 1 year old (70.0%) and mates affected 2.3 times as much as females. The trunk and distal extremities are the most common site of urticaria pigmentosa and mastocytoma respectively. CD117 was strongly positive in all cases of utricaria pigmentosa (both child and adult type) and mastocytoma. Conclusion : Urticaria pigmentosa of infantile onset was the most common, followed by infantile mastocytoma. Systemic reactive manifestations are rate in cutaneous mastocytosis. The strong expression of CD117 was seen regardless of cutancous mastocytoses.
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      Background : Mastoeytosis is characterized by accumulation of mast cells in various organs, most frequently in skin. Cutaneous mastoeytosis is a relatively rare disease in outpatient clinics and the clinicopathological study has not been done yet in K...

      Background : Mastoeytosis is characterized by accumulation of mast cells in various organs, most frequently in skin. Cutaneous mastoeytosis is a relatively rare disease in outpatient clinics and the clinicopathological study has not been done yet in Korea. Objective : The ain of this study is to analyse the clinieopathological features of cutaneous mastocytosis. In addition, we examined CDU7 expression in the skin biopsy specimens immunohistochemically Methods : Thirty cases of cutaneous mastocytosis were collected from 1990 to 1999 in Asan Medical Center. Clinical records, photographs. and biopsy slides were reviewed. In each biopsy specimen, CDU7 was stained by immunoperoxidase method. Results : Among 30 cases, 29 cases were childhood type urticaria pigmeniosa(76.7 %) or mastocytoma(20.2%) and only I case occurred after 16 years of age. The incidence showed a peak under 1 year old (70.0%) and mates affected 2.3 times as much as females. The trunk and distal extremities are the most common site of urticaria pigmentosa and mastocytoma respectively. CD117 was strongly positive in all cases of utricaria pigmentosa (both child and adult type) and mastocytoma. Conclusion : Urticaria pigmentosa of infantile onset was the most common, followed by infantile mastocytoma. Systemic reactive manifestations are rate in cutaneous mastocytosis. The strong expression of CD117 was seen regardless of cutancous mastocytoses.

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