The Current Status of SPECT or SPECT/CT in South Korea

다국어 초록 (Multilingual Abstract)

The first step to nuclear medicine in Korea startedwith introduction of the gamma camera in 1969. Althoughplanar images with the gamma camera give important functionalinformation, they have the limitations that result from 2-dimensional images. Single-photon emission computed tomography(SPECT) due to its 3-dimensional image acquisition issuperior to earlier planar gamma imaging in image resolutionand diagnostic accuracy. As demand for a hybrid functional andanatomical imaging device has increased, integrated SPECT/CT systems have been used. In Korea, SPECT/CT was for thefirst time installed in 2003. SPECT/CT can eliminate manypossible pitfalls on SPECT-alone images, making better attenuationcorrection and thereby improving image quality.
Therefore, SPECT/CT is clinically preferred in many hospitalsin various aspects.More recently, additional SPECT/CT imagestaken from the region with equivocal uptake on planar imageshave been helpful in making precise interpretation as part oftheir clinical workup in postoperative thyroid cancer patients.
SPECT and SPECT/CT have various advantages, but its clinicalapplication has gradually decreased in recent few years.
While some researchers investigated the myocardial blood flowwith cardiac PET using F-18 FDG or N-13 ammonia, myocardialperfusion SPECT is, at present, the radionuclide imagingstudy of choice for the risk stratification and guiding therapy inthe coronary artery disease patients in Korea. New diagnosticradiopharmaceuticals for AD have received increasingattention; nevertheless, brain SPECT will remain the most reliablemodality evaluating cerebral perfusion.

참고문헌 (Reference)

1 김재승, "도파민 운반체 영상의 임상이용을 위한 실제적 접근" 대한핵의학회 42 (42): 425-432, 2008

2 Xue YL, "Value of(131)I SPECT/CT for the evaluation of differentiated thyroid cancer : a systematic review of the literature" 40 : 768-778, 2013

3 권수현, "The Utility of Segmental Analysis in Cardiac I-123MIBG SPECT in Parkinson’s Disease" 대한핵의학회 49 (49): 298-302, 2015

4 나창주, "The Clinical Value of Hybrid Sentinel Lymphoscintigraphy to Predict Metastatic Sentinel Lymph Nodes in Breast Cancer" 대한핵의학회 49 (49): 26-32, 2015

5 Medicine TPCottAoKSoN, "The 50th Anniversary of the Korean Society of Nuclear Medicine" 2011

6 Linke R, "Skeletal SPECT/CT of the peripheral extremities" 194 : W329-W335, 2010

7 Raynaud C, "SPECTanalysis of recent cerebral infarction" 20 : 192-204, 1989

8 Even-Sapir E, "SPECT/multislice low-dose CT : a clinically relevant constituent in the imaging algorithm of nononcologic patients referred for bone scintigraphy" 48 : 319-324, 2007

9 Krausz Y, "SPECT/CT hybrid imaging with 111In-pentetreotide in assessment of neuroendocrine tumours" 59 : 565-573, 2003

10 Berman D, "Risk stratification in coronary artery disease : implications for stabilization and prevention" 79 : 10-16, 1997

11 Jimenez-Heffernan A, "Results of a prospective International Atomic Energy Ahency(IAEA)sentinel node trial on the value of SPECT/CT over planar imaging in various malignancies" 56 : 1338-1344, 2015

12 Hougaard K, "Regional cerebral blood flow in focal cortical epilepsy" 33 : 527-535, 1976

13 Avram AM, "Radioiodine scintigraphy with SPECT/CT : an important diagnostic tool for thyroid cancer staging and risk stratification" 42 : 170-180, 2014

14 Shaw LJ, "Prognostic value of normal exercise and adenosine(99m)Tc-tetrofosmin SPECT imaging : results from the multicenter registry of 4728 patients" 44 : 134-139, 2003

15 최홍윤, "Parametric Cerebrovascular Reserve Images Using Acetazolamide 99mTc-HMPAO SPECT: A Feasibility Study of Quantitative Assessment" 대한핵의학회 47 (47): 188-195, 2013

16 Jacobson AF, "Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study" 55 : 2212-2221, 2010

17 Berman DS, "Incremental value of prognostic testing in patients with known or suspected ischemic heart disease : a basis for optimal utilization of exercise technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography" 26 : 639-647, 1995

18 "Data library on Nuclear Medicine Facilities and Procedures in Korea" The Korean Society of Nuclear Medicine

19 Lee DS, "Comparison of the cost-effectiveness of stress myocardial SPECT and stress echocardiography in suspected coronary artery disease considering the prognostic value of false-negative results" 9 : 515-522, 2002

20 Van Binnebeek S, "Comparison of diagnostic accuracy of Inpentetreotide SPECT and Ga-DOTATOC PET/CT : a lesion-bylesion analysis in patients with metastatic neuroendocrine tumours" 26 : 900-909, 2016

21 Patterson RE, "Comparison of costeffectiveness and utility of exercise ECG, single photon emission computed tomography, positron emission tomography, and coronary angiography for diagnosis of coronary artery disease" 91 : 54-65, 1995

22 Oh JK, "Comparison of I-123 MIBG planar imaging and SPECT for the detection of decreased heart uptake in Parkinson disease" 2015

23 이인기, "Comparison of Diagnostic Sensitivity and Quantitative Indices Between 68Ga-DOTATOC PET/CT and 111In-Pentetreotide SPECT/CT in Neuroendocrine Tumors: a Preliminary Report" 대한핵의학회 49 (49): 284-290, 2015

24 Huellner MW, "Clinical applications of SPECT/CT in imaging the extremities" 41 (41): S50-S58, 2014

25 Boogers MJ, "Cardiac sympathetic denervation assessed with 123-iodine metaiodobenzylguanidine imaging predicts ventricular arrhythmias in implantable cardioverterdefibrillator patients" 55 : 2769-2777, 2010

26 Marshall A, "Cardiac iodine-123 metaiodobenzylguanidine imaging predicts ventricular arrhythmia in heart failure patients receiving an implantable cardioverter-defibrillator for primary prevention" 98 : 1359-1365, 2012

27 Germano G, "Automatic quantitation of regional myocardial wall motion and thickening from gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomography" 30 : 1360-1367, 1997

28 Rozovsky K, "Added value of SPECT/CT for correlation ofMIBG scintigraphy and diagnostic CT in neuroblastoma and pheochromocytoma" 190 : 1085-1090, 2008

29 Germano G, "A new algorithm for the quantitation of myocardial perfusion SPECT. I: technical principles and reproducibility" 41 : 712-719, 2000

30 Davison CM, "A comparison of FDG-PET and blood flow SPECT in the diagnosis of neurodegenerative dementias : a systematic review" 29 : 551-561, 2014