P-11 Diagnostic accuracy of qSOFA, SIRS, and early warning scores for diagnosis of septic shock = P-11 Diagnostic accuracy of qSOFA, SIRS, and early warning scores for diagnosis of septic shock

다국어 초록 (Multilingual Abstract)

Objectives: We evaluated diagnostic accuracy of quick Sequential Organ Failure Assessment (qSOFA), Systemic Inflammatory Response Syndrome (SIRS) criteria, Modified Early Warning Score (MEWS), and National Early Warning Score (NEWS) for diagnosis of septic shock within 24hrs of emergency department (ED) arrival
Methods: We retrospectively analyzed 618 patients who admitted to medical intensive care unit via ED between July 2014 and June 2017. Each score was calculated when patients arrived at ED. The definition of septic shock was based on sepsis-3 criteria.
Results: The enroll patients had a median age of 69.0 years, and 63.6% were male. Septic shock was diagnosed in 150 (24.3%) patients. The area under the receiver operation characteristic curves (AUROC) for qSOFA, SIRS criteria, MEWS, and NEWS were 0.671 (95% CI 0.623-0.720), 0.603 (0.552-0.654), 0.724 (0.679-0.769), and 0.674 (0.624-0.722), respectively. The AUROC of MEWS was significantly higher than other scores (p＜0.05). Further analysis using common thresholds for each score (qSOFA ≥2, SIRS criteria≥2, MEWS≥5, NEWS≥8) indicated the diagnosis of septic shock were 36.3, 27.9, 37.6, and 31.1%, respectively.
Conclusions: In our study, MEWS would be associated with higher diagnostic accuracy of septic shock compared with qSOFA, SIRS, and NEWS.