Introduction: Long term clinical outcomes such as 1-year survival rate are gaining attention due to an increase in ICU short term survival rate. Sarcopenia and ICU acquired weakness is known to affect ventilator weaning and rehabilitation. Measurement...
Introduction: Long term clinical outcomes such as 1-year survival rate are gaining attention due to an increase in ICU short term survival rate. Sarcopenia and ICU acquired weakness is known to affect ventilator weaning and rehabilitation. Measurement of rectus femoris muscle is known to be reliable in recognizing sarcopenia. If the patients have sarcopenia, they have limited performance and negative effects on respiratory capacity.
Method: Fourty nine patients who were hospitalized for more than a week in ICU were enrolled prospectively. Rectus femoris muscle cross sectional area(CSA) was measured at seventh day after admission to the ICU by ultrasound. The correlation between rectus femoris muscle CSA and clinical outcomes were analyzed by Pearson coefficient, partial correlation coefficient.
Result: Rectus femoris muscle CSA showed significant negative correlation with hospital day even when age, gender, BMI, APACHE II score are controlled. (P=0.001) The duration of the ventilator application and ICU day were also correlated with rectus femoris muscle CSA but not statistically significant. (P=0.241), (p=0.201)
Conclusion: Early ultrasound measurement of rectus femoris muscle CSA in ICU can predict clinical outcomes, especially long term clinical outcomes.