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      Effects of a Health Drink Containing the Extract of the Hovenia Dulcis Fruit Stalk and Theracurmin, on Ethanol-Induced Hangover

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      https://www.riss.kr/link?id=A108151998

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      다국어 초록 (Multilingual Abstract)

      The fruit stalk of Hovenia dulcis (H.dulcis) is traditionally used to relieve hangovers in Korea. Theracurmin is a highlyabsorbable curcumin preparation which increases the bioavailability of curcumin. Curcumin is known for its antioxidant andanti-inf...

      The fruit stalk of Hovenia dulcis (H.dulcis) is traditionally used to relieve hangovers in Korea. Theracurmin is a highlyabsorbable curcumin preparation which increases the bioavailability of curcumin. Curcumin is known for its antioxidant andanti-inflammatory effects. However, the role of this combination in lowering alcohol levels in the body, thereby alleviatingthe severity of alcohol-induced hangover has not been investigated. Therefore, we conducted a study to investigate theeliminatory effects of a health drink containing the extract of the H. dulcis fruit stalk and theracurmin (theracurmin drink) onethanol-induced hangover in rats. The theracurmin drink delivered orally to rats 30 mins before the administration of 40%ethanol (5 g/kg body weight), lowered the concentration of ethanol and acetaldehyde in the blood samples collected 1, 3,and 5 h after ethanol administration. Furthermore, the theracurmin drink increased the activities of alcohol dehydrogenaseand aldehyde dehydrogenase enzymes. The effectiveness of the theracurmin drink was thus superior to that of other healthdrink products, suggesting that its consumption may alleviate or prevent an alcohol-induced hangover.

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      참고문헌 (Reference)

      1 동미숙, "헛개나무(Hovenia dulcis var. koreana) 과병 열수추출분획물의 간보호 및 혈중 알콜 저하 작용" 대한약학회 48 (48): 34-40, 2004

      2 박은미, "헛개나무 열매 추출물을 함유한 건강음료의 숙취 제거 효과" 한국식생활문화학회 21 (21): 71-75, 2006

      3 Coppersmith V, "The use of N-acetylcysteine in the prevention of hangover: a randomized trial" 11 (11): 13397-, 2021

      4 Thulin P, "The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes:Correlation with serum ALT levels" 38 (38): 961-968, 2016

      5 Bucher T, "Specific photometric determination of ethyl alcohol based on an enzymatic reaction" 29 (29): 615-616, 1951

      6 신선미, "SM-2015의 혈중 알코올 분해 및 숙취 개선 효과" 대한한방내과학회 38 (38): 20-31, 2017

      7 Kato S, "Role of xanthine oxidase in ethaol-induced lipid peroxidation in rat" 98 (98): 203-210, 1990

      8 Prat G, "Neurocognitive effects of alcohol hangover" 33 (33): 15-23, 2008

      9 Ohno M, "Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells" 12 (12): e0185999-, 2017

      10 Seitz HK, "Molecular mechanisms of alcoholmediated carcinogenesis" 7 (7): 599-612, 2007

      1 동미숙, "헛개나무(Hovenia dulcis var. koreana) 과병 열수추출분획물의 간보호 및 혈중 알콜 저하 작용" 대한약학회 48 (48): 34-40, 2004

      2 박은미, "헛개나무 열매 추출물을 함유한 건강음료의 숙취 제거 효과" 한국식생활문화학회 21 (21): 71-75, 2006

      3 Coppersmith V, "The use of N-acetylcysteine in the prevention of hangover: a randomized trial" 11 (11): 13397-, 2021

      4 Thulin P, "The peroxisome proliferator-activated receptor α agonist, AZD4619, induces alanine aminotransferase-1 gene and protein expression in human, but not in rat hepatocytes:Correlation with serum ALT levels" 38 (38): 961-968, 2016

      5 Bucher T, "Specific photometric determination of ethyl alcohol based on an enzymatic reaction" 29 (29): 615-616, 1951

      6 신선미, "SM-2015의 혈중 알코올 분해 및 숙취 개선 효과" 대한한방내과학회 38 (38): 20-31, 2017

      7 Kato S, "Role of xanthine oxidase in ethaol-induced lipid peroxidation in rat" 98 (98): 203-210, 1990

      8 Prat G, "Neurocognitive effects of alcohol hangover" 33 (33): 15-23, 2008

      9 Ohno M, "Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells" 12 (12): e0185999-, 2017

      10 Seitz HK, "Molecular mechanisms of alcoholmediated carcinogenesis" 7 (7): 599-612, 2007

      11 Lee HI, "Low doses of curcumin protect alcohol-induced liver damage by modulation of the alcohol metabolic pathway, CYP2E1and AMPK" 93 (93): 693-699, 2013

      12 Cho JY, "Isolation and identification of 3-methoxy-4-hydroxybenzoic acid and 3-methoxy- 4-hydroxycinnamic acid from hot water extracts of Hovenia dulcis Thunb and confirmation of their antioxidative and antimicrobial activity" 32 (32): 1403-1408, 2000

      13 Jayawardena R, "Interventions for treatment and/or prevention of alcohol hangover: Systematic review" 32 (32): e2600-, 2017

      14 Piasecki TM, "Hangover frequency and risk for alcohol use disorders:evidence from a longitudinal high-risk study." 114 (114): 223-234, 2005

      15 Jae Young Jang, "Epidemiology of alcoholic liver disease in Korea" 대한간학회 24 (24): 93-99, 2018

      16 Lee HS, "Effect of Korean pear (Pyruspyrifolia cv. Shingo)juice on hangover severity following alcohol consumption" 58 : 101-106, 2013

      17 Torruellas C, "Diagnosis of alcoholic liver disease" 20 (20): 11684-11699, 2014

      18 Lundquist F, "Determination with aldehyde dehydrogenase" 3 : 1509-1513, 1974

      19 Lee MK, "Biological activity of Hovenia dulcis Thunb" 7 (7): 185-192, 1999

      20 Masayuki Y, "Bioactive constituents of Chinese natural medicines. III. Absolute stereostructures of new dihydroflavonols, hovenitins I, II, and III, isolated from hoveniae semen seu fructus, the seed and fruit of Hovenia dulcis THUNB. (Rhamnaceae): inhibitory effect on alcohol-induced muscular relaxation and hepatoprotective activity" 117 (117): 108-118, 1997

      21 백진경, "Anti-Oxidant Effects of Highly Bioavailable Curcumin Powder in High-Fat Diet Fed- and Streptozotocin-Induced Type 2 Diabetic Rats" 한국식품영양학회 32 (32): 133-137, 2019

      22 Swift R, "Alcohol hangover: mechanisms and mediators" 22 (22): 54-60, 1998

      23 Foster, WH, "Absenteeism and business costs:does substance abuse matter" 28 (28): 27-33, 2005

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
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      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2014-12-16 학술지명변경 외국어명 : Journal of The Korean Society of Dietary Culture -> Journal of The Korean Society of Food Culture KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2004-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보 1차 FAIL (등재후보1차) KCI등재후보
      2002-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.8 0.8 0.87
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.87 0.89 1.461 0.11
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