Chlorfenapyr-Induced Toxic Leukoencephalopathy with Radiologic Reversibility: A Case Report and Literature Review

다국어 초록 (Multilingual Abstract)

Chlorfenapyr is a widely used, moderately hazardous pesticide. Previous reports have indicated that chlorfenapyr intoxication can be fatal in humans. We reported the first non-fatal case of chlorfenapyr-induced toxic leukoencephalopathy in a 44-year-old female with resolution of extensive and abnormal signal intensities in white matter tracts throughout the brain, brain stem, and spinal cord on serial magnetic resonance imaging.

참고문헌 (Reference)

1 Keogh CF, "Neuroimaging features of heroin inhalation toxicity: “chasing the dragon”" 180 : 847-850, 2003

2 Choi UT, "Fatality from acute chlorfenapyr poisoning" 48 : 458-459, 2010

3 Sivasubramanian S, "Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: a report of two cases" 20 : 192-194, 2010

4 Tharaknath VR, "Clinical and radiological findings in chlorfenapyr poisoning" 16 : 252-254, 2013

5 United States Environmental Protection Agency, "Chlorfenapyr Reason for Issuance: New Chemical Registration"

6 United States Environmental Protection Agency, "Chlorfenapyr - 129093: Health Effects Division Risk Characterization for Use of the Chemical Chlorfenapyr (Alert, EPA File Symbol 5905-GAI) in/on Citrus (6F04623)"

7 McKinney AM, "Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging" 193 : 192-206, 2009

8 Kang C, "A patient fatality following the ingestion of a small amount of chlorfenapyr" 7 : 239-241, 2014

9 Ku JE, "A case of survival after chlorfenapyr intoxication with acute pancreatitis" 2 : 63-66, 2015

10 Kwon JS, "A case of chlorfenapyr intoxication with central nervous system involvement" 2 : 147-, 2012