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      목시플록사신만으로 치료된 푸사륨 진균 각막염 1예 = A Case of Fusarium Keratitis Treated with Moxifloxacin 0.5% Ophthalmic Solution

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      https://www.riss.kr/link?id=A100524234

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      다국어 초록 (Multilingual Abstract)

      Purpose: To report a case of fusarium keratitis treated with only moxifloxacin 0.5% ophthalmic solution (Vigamox?, Alcon Laboratories, Inc., Ft Worth, TX, USA). Case summary: A 37- year- old healthy male patient experienced a right eye injury due to grain 7 days prior to presentation at our hospital with visual disturbance and ocular pain. A 2.7 × 4.3 mm sized corneal epithelial defect with irregular featherlike midstromal infiltration was observed, and slit lamp examination revealed a dry, rough texture. Thus a smear and culture were performed. Moxifloxacin 0.5% ophthalmic solution (Vigamox?) and lubricant were applied for treatment. Three days after using the eye solution, all clinical features improved. Seven days later, Fusarium species was identified in culture. Conclusions: As standard treatment for Fusarium, the authors of the present study used an antifungal agent. Although hyphae were detected in culture, the use of only moxifloxacin 0.5% ophthalmic solution (Vigamox?) result in a satisfactory result and improvement in clinical features. J Korean Ophthalmol Soc 2012;53(2):338-341
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      Purpose: To report a case of fusarium keratitis treated with only moxifloxacin 0.5% ophthalmic solution (Vigamox?, Alcon Laboratories, Inc., Ft Worth, TX, USA). Case summary: A 37- year- old healthy male patient experienced a right eye injury due to g...

      Purpose: To report a case of fusarium keratitis treated with only moxifloxacin 0.5% ophthalmic solution (Vigamox?, Alcon Laboratories, Inc., Ft Worth, TX, USA). Case summary: A 37- year- old healthy male patient experienced a right eye injury due to grain 7 days prior to presentation at our hospital with visual disturbance and ocular pain. A 2.7 × 4.3 mm sized corneal epithelial defect with irregular featherlike midstromal infiltration was observed, and slit lamp examination revealed a dry, rough texture. Thus a smear and culture were performed. Moxifloxacin 0.5% ophthalmic solution (Vigamox?) and lubricant were applied for treatment. Three days after using the eye solution, all clinical features improved. Seven days later, Fusarium species was identified in culture. Conclusions: As standard treatment for Fusarium, the authors of the present study used an antifungal agent. Although hyphae were detected in culture, the use of only moxifloxacin 0.5% ophthalmic solution (Vigamox?) result in a satisfactory result and improvement in clinical features. J Korean Ophthalmol Soc 2012;53(2):338-341

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      참고문헌 (Reference)

      1 이광훈, "진균각막염에서 치료실패의 위험인자에 대한 분석" 대한안과학회 49 (49): 737-742, 2008

      2 O’Day DM, "Selection of appropriate antifungal therapy" 6 : 238-245, 1987

      3 Wong TY, "Risk factors and clinical outcomes between fungal and bacterial keratitis: a comparative study" 23 : 275-281, 1997

      4 Thomas PA, "Mycotic keratitis--an underestimated mycosis" 32 : 235-256, 1994

      5 Nitiss JL, "Investigating the biological functions of DNA topoisomerases in eukaryotic cells" 1400 : 63-81, 1998

      6 O’Day DM, "Influence of corticosteroid on experimentally induced keratomycosis" 109 : 1601-1604, 1991

      7 Dalhoff A, "Immunomodulatory effects of quinolones" 3 : 359-371, 2003

      8 Verma S, "Fusarium solani keratitis following LASIK for myopia" 86 : 1190-1191, 2002

      9 Srinivasan M., "Fungal keratitis" 15 : 321-327, 2004

      10 O’Day DM, "Efficacy of antifungal agents in the cornea. II. Influence of corticosteroids" 25 : 331-335, 1984

      1 이광훈, "진균각막염에서 치료실패의 위험인자에 대한 분석" 대한안과학회 49 (49): 737-742, 2008

      2 O’Day DM, "Selection of appropriate antifungal therapy" 6 : 238-245, 1987

      3 Wong TY, "Risk factors and clinical outcomes between fungal and bacterial keratitis: a comparative study" 23 : 275-281, 1997

      4 Thomas PA, "Mycotic keratitis--an underestimated mycosis" 32 : 235-256, 1994

      5 Nitiss JL, "Investigating the biological functions of DNA topoisomerases in eukaryotic cells" 1400 : 63-81, 1998

      6 O’Day DM, "Influence of corticosteroid on experimentally induced keratomycosis" 109 : 1601-1604, 1991

      7 Dalhoff A, "Immunomodulatory effects of quinolones" 3 : 359-371, 2003

      8 Verma S, "Fusarium solani keratitis following LASIK for myopia" 86 : 1190-1191, 2002

      9 Srinivasan M., "Fungal keratitis" 15 : 321-327, 2004

      10 O’Day DM, "Efficacy of antifungal agents in the cornea. II. Influence of corticosteroids" 25 : 331-335, 1984

      11 Jay HK, "Cornea and External Disease: Clinical Diagnosis and Management" CV Mosby 1253-1265, 1997

      12 Whitcher JP, "Coneal blindness: a global perspective" 79 : 214-221, 2001

      13 Munir WM, "Clinical response of contact lens-associated fungal keratitis to topical fluoroquinolone theraphy" 26 : 621-624, 2007

      14 김윤상, "Chromomycetes 에 의한 진균성 각막염" 대한안과학회 44 (44): 33-759, 2003

      15 Day S, "Activity of antibiotics against Fusarium and Aspergillus" 93 : 116-119, 2009

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      2016 0.22 0.22 0.22
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