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      상악동 내 전이성 신세포암에 대한 Tyrosine Kinase 억제제 치료 경험 1예 = A Case of Metastatic Renal Cell Carcinoma to the Maxillary Sinus Treated with Tyrosine Kinase Inhibitor

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      https://www.riss.kr/link?id=A101611139

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      다국어 초록 (Multilingual Abstract)

      Renal cell carcinoma is a rare metastatic malignant neoplasm of the paranasal sinus. The clinical picture and radiologic findings might sometimes be insufficient to suspect metastatic renal cell carcinoma. Therefore, the definite diagnosis should be made according to the result of intra-operative biopsy. Recently, tyrosine kinase inhibitor, sunitinib, is considered as an effective agent in the treatment of metastatic renal cell carcinoma. We report a case of 69-year-old patient with metastatic renal cell carcinoma of the right maxillary sinus with accompanying fungal sinusitis. After 6 times of chemotherapy with sunitinib malate, there was no sign of recurrence or local advancement of the tumor during the 1-year follow-up period.
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      Renal cell carcinoma is a rare metastatic malignant neoplasm of the paranasal sinus. The clinical picture and radiologic findings might sometimes be insufficient to suspect metastatic renal cell carcinoma. Therefore, the definite diagnosis should be m...

      Renal cell carcinoma is a rare metastatic malignant neoplasm of the paranasal sinus. The clinical picture and radiologic findings might sometimes be insufficient to suspect metastatic renal cell carcinoma. Therefore, the definite diagnosis should be made according to the result of intra-operative biopsy. Recently, tyrosine kinase inhibitor, sunitinib, is considered as an effective agent in the treatment of metastatic renal cell carcinoma. We report a case of 69-year-old patient with metastatic renal cell carcinoma of the right maxillary sinus with accompanying fungal sinusitis. After 6 times of chemotherapy with sunitinib malate, there was no sign of recurrence or local advancement of the tumor during the 1-year follow-up period.

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      참고문헌 (Reference)

      1 우현재, "비강과 구강저에 발생한 전이성 신세포암 1예" 대한이비인후과학회 51 (51): 380-383, 2008

      2 Homer JJ, "The role of endoscopy in the management of nasal neoplasia" 11 (11): 41-47, 1997

      3 Motzer RJ, "Sunitinib versus interferon alfa in metastatic renal-cell carcinoma" 356 (356): 115-124, 2007

      4 Gore ME, "Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial" 10 (10): 757-763, 2009

      5 Dineen MK, "Results of surgical treatment of renal cell carcinoma with solitary metastasis" 140 (140): 277-279, 1988

      6 Onufrey V, "Radiation therapy in the treatment of metastatic renal cell carcinoma" 11 (11): 2007-2009, 1985

      7 Madison JF, "Pathologic quiz case 2. Clear cell carcinoma, consistent with metastatic renal cell carcinoma" 114 (114): 570-573., 1988

      8 Gottlieb MD, "Paradoxical spread of renal cell carcinoma to the head and neck" 108 (108): 1301-1305, 1998

      9 DiBiase SJ, "Palliative irradiation for focally symptomatic metastatic renal cell carcinoma: support for dose escalation based on a biological model" 158 (158): 746-749, 1997

      10 Simo R, "Metastatic renal cell carcinoma to the nose and paranasal sinuses" 22 (22): 722-727, 2000

      1 우현재, "비강과 구강저에 발생한 전이성 신세포암 1예" 대한이비인후과학회 51 (51): 380-383, 2008

      2 Homer JJ, "The role of endoscopy in the management of nasal neoplasia" 11 (11): 41-47, 1997

      3 Motzer RJ, "Sunitinib versus interferon alfa in metastatic renal-cell carcinoma" 356 (356): 115-124, 2007

      4 Gore ME, "Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial" 10 (10): 757-763, 2009

      5 Dineen MK, "Results of surgical treatment of renal cell carcinoma with solitary metastasis" 140 (140): 277-279, 1988

      6 Onufrey V, "Radiation therapy in the treatment of metastatic renal cell carcinoma" 11 (11): 2007-2009, 1985

      7 Madison JF, "Pathologic quiz case 2. Clear cell carcinoma, consistent with metastatic renal cell carcinoma" 114 (114): 570-573., 1988

      8 Gottlieb MD, "Paradoxical spread of renal cell carcinoma to the head and neck" 108 (108): 1301-1305, 1998

      9 DiBiase SJ, "Palliative irradiation for focally symptomatic metastatic renal cell carcinoma: support for dose escalation based on a biological model" 158 (158): 746-749, 1997

      10 Simo R, "Metastatic renal cell carcinoma to the nose and paranasal sinuses" 22 (22): 722-727, 2000

      11 Lee HM, "Metastatic renal cell carcinoma presenting as epistaxis" 262 (262): 69-71, 2005

      12 Som PM, "Metastatic hypernephroma to the head and neck" 8 : 1103-1106, 1987

      13 Saitoh H, "Distant metastasis of renal adenocarcinoma" 48 (48): 1487-1491, 1981

      14 Skinner DG, "Diagnosis and management of renal cell carcinoma. A clinical and pathologic study of 309 cases" 28 (28): 1165-1177, 1971

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