궤양성 대장염에 동반된 간정맥 혈전증 1예 = A Case of Hepatic Vein Thrombosis Associated with Ulcerative Colitis

다국어 초록 (Multilingual Abstract)

Patients with inflammatory bowel disease are known to have hypercoagulability and an increased risk for venous thromboembolism. The deep veins of the lower extremities and the pulmonary veins are the most common sites of thrombosis in ulcerative colitis. However, hepatic vein thrombosis (Budd-Chiari syndrome) is a very rare extra-intestinal complication of ulcerative colitis in children. We describe a case of hepatic vein thrombosis in a 15-year-old girl with ulcerative colitis who presented with abdominal pain and hematochezia. Doppler ultrasonography and an abdominal CT scan revealed the characteristic filling defects caused by large thrombi in both hepatic veins. These lesions were successfully treated with conventional management for ulcerative colitis and anticoagulation therapy.

참고문헌 (Reference)

1 정록선, "궤양성 대장염에 합병된 Budd-Chiari 증후군 및 대장암 1예" 대한소화기내시경학회 28 (28): 326-331, 2004

2 박소영, "궤양성 대장염에 동반된 Budd-Chiari 증후군 및 상장간막정맥 혈전증 1예" 대한소화기학회 45 (45): 201-205, 2005

3 Graef V, "Venous thrombosis occurring with nonspecific ulcerative colitis" 117 : 377-382, 1966

4 Talbot RW, "Vascular complications of inflammatory bowel disease" 61 : 140-145, 1986

5 Rahhal RM, "Ulcerative colitis complicated by ischemic colitis and Budd-Chiari: case report" 40 : 94-97, 2005

6 Chesner I, "Ulcerative colitis complicated by Budd-Chiari syndrome" 27 : 1096-1100, 1986

7 Jackson LM, "Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and factor V Leiden" 90 : 183-188, 1997

8 Kelsey MP, "Occlusion of the hepatic veins. A review of 20 cases" 75 : 175-183, 1945

9 Parker RG, "Occlusion of the hepatic vein in man" 38 : 369-402, 1959

10 Grip O, "Inflammatory bowel disease promotes venous thrombosis earlier in life" 35 : 691-623, 2000

11 Lee JC, "Hypercoagulability associated with chronic ulcerative colitis: changes in blood coagulation factors" 54 : 76-84, 1968

12 Socha P, "Hepatic vein thrombosis as a complication of ulcerative colitis in a 12-year-old patient" 52 : 1293-1298, 2007

13 Kraut J, "Hepatic vein thrombosis (Budd-Chiari syndrome) in an adolescent with ulcerative colitis" 25 : 417-420, 1997

14 Mosen U, "Extracolonic diagnoses in ulcerative colitis: an epidemiological study" 85 : 711-716, 1990

15 Gentil-Kocher S, "Budd-Chiari syndrome in children: report of 22 cases" 113 : 30-38, 1988

16 Tilanus HW, "Budd-Chiari syndrome" 82 : 1023-1030, 1995

17 Frank J, "Budd-Chiari shndrome: early intervention with angioplasty and thrombolytic therapy" 69 : 877-881, 1994