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      20세 이상 한국인에서 상대 악력과 공복혈당장애와의 관련성 = The Association of Relative Handgrip Strength with Impaired Fasting Glucose among Koreans Aged more than 20 Years Old

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      https://www.riss.kr/link?id=A106837247

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      다국어 초록 (Multilingual Abstract)

      Background: The prevalence of impaired fasting glucose (IFG) in Korea is increasing. Few studies have investigated the relationship between handgrip strength (HGS) and type 2 diabetes among Koreans; however, no study has investigated the relationship between IFG and HGS among Koreans. Therefore, we examined the relationship between relative IFG and HGS to evaluate HGS as a marker of prediabetes.
      Methods: This cross-sectional study analyzed data from participants aged 20 years or older (n=9,190) who did not have diabetes and had had their body mass index, fasting plasma glucose (FPG), and HGS measured in the 2016–2017 Korea National Health and Nutrition Examination Survey. The association between relative HGS and IFG was analyzed using complex sample logistic regression analyses after adjusting for age, education, strengthening exercise, aerobic exercise, smoking, excessive drinking, and chronic diseases.
      Results: The prevalence of IFG was 31.5 (0.9)% and 19.6 (0.7)% for men and women, respectively. According to the increase in quartile of relative HGS, FPG and HbA1c significantly decreased in both men and women (Ptrend<0.001). In multivariate logistic regression, the odds of IFG significantly decreased with the increase in quartile of relative HGS in both men and women (Ptrend=0.001 for men, Ptrend=0.002 for women).
      Conclusion: This population-based, nationally representative study suggests that higher relative HGS is associated with a decreased risk of IFG for both men and women.
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      Background: The prevalence of impaired fasting glucose (IFG) in Korea is increasing. Few studies have investigated the relationship between handgrip strength (HGS) and type 2 diabetes among Koreans; however, no study has investigated the relationship ...

      Background: The prevalence of impaired fasting glucose (IFG) in Korea is increasing. Few studies have investigated the relationship between handgrip strength (HGS) and type 2 diabetes among Koreans; however, no study has investigated the relationship between IFG and HGS among Koreans. Therefore, we examined the relationship between relative IFG and HGS to evaluate HGS as a marker of prediabetes.
      Methods: This cross-sectional study analyzed data from participants aged 20 years or older (n=9,190) who did not have diabetes and had had their body mass index, fasting plasma glucose (FPG), and HGS measured in the 2016–2017 Korea National Health and Nutrition Examination Survey. The association between relative HGS and IFG was analyzed using complex sample logistic regression analyses after adjusting for age, education, strengthening exercise, aerobic exercise, smoking, excessive drinking, and chronic diseases.
      Results: The prevalence of IFG was 31.5 (0.9)% and 19.6 (0.7)% for men and women, respectively. According to the increase in quartile of relative HGS, FPG and HbA1c significantly decreased in both men and women (Ptrend<0.001). In multivariate logistic regression, the odds of IFG significantly decreased with the increase in quartile of relative HGS in both men and women (Ptrend=0.001 for men, Ptrend=0.002 for women).
      Conclusion: This population-based, nationally representative study suggests that higher relative HGS is associated with a decreased risk of IFG for both men and women.

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      참고문헌 (Reference)

      1 Carson BP, "The potential role of contraction-induced myokines in the regulation of metabolic function for the prevention and treatment of type 2 diabetes" 8 : 97-, 2017

      2 Herman WH, "The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance" 142 : 323-332, 2005

      3 van der Kooi AL, "The association of handgrip strength and type 2 diabetes mellitus in six ethnic groups : an analysis of the HELIUS study" 10 : e0137739-, 2015

      4 McGrath R, "The association between muscle weakness and incident diabetes in older Mexican Americans" 18 : 452.e7-452.e12, 2017

      5 Holten MK, "Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes" 53 : 294-305, 2004

      6 Merry TL, "Skeletal muscle glucose uptake during exercise : a focus on reactive oxygen species and nitric oxide signaling" 61 : 479-484, 2009

      7 Li D, "Relative handgrip strength is inversely associated with metabolic profile and metabolic disease in the general population in China" 9 : 59-, 2018

      8 Hu S, "Relationship between grip strength and prediabetes in a large-scale adult population" 56 : 844-851, 2019

      9 Irvine C, "Progressive resistance exercise improves glycaemic control in people with type 2 diabetes mellitus : a systematic review" 55 : 237-246, 2009

      10 Tuomilehto J, "Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance" 344 : 1343-1350, 2001

      1 Carson BP, "The potential role of contraction-induced myokines in the regulation of metabolic function for the prevention and treatment of type 2 diabetes" 8 : 97-, 2017

      2 Herman WH, "The cost-effectiveness of lifestyle modification or metformin in preventing type 2 diabetes in adults with impaired glucose tolerance" 142 : 323-332, 2005

      3 van der Kooi AL, "The association of handgrip strength and type 2 diabetes mellitus in six ethnic groups : an analysis of the HELIUS study" 10 : e0137739-, 2015

      4 McGrath R, "The association between muscle weakness and incident diabetes in older Mexican Americans" 18 : 452.e7-452.e12, 2017

      5 Holten MK, "Strength training increases insulin-mediated glucose uptake, GLUT4 content, and insulin signaling in skeletal muscle in patients with type 2 diabetes" 53 : 294-305, 2004

      6 Merry TL, "Skeletal muscle glucose uptake during exercise : a focus on reactive oxygen species and nitric oxide signaling" 61 : 479-484, 2009

      7 Li D, "Relative handgrip strength is inversely associated with metabolic profile and metabolic disease in the general population in China" 9 : 59-, 2018

      8 Hu S, "Relationship between grip strength and prediabetes in a large-scale adult population" 56 : 844-851, 2019

      9 Irvine C, "Progressive resistance exercise improves glycaemic control in people with type 2 diabetes mellitus : a systematic review" 55 : 237-246, 2009

      10 Tuomilehto J, "Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance" 344 : 1343-1350, 2001

      11 Tabák AG, "Prediabetes : a high-risk state for diabetes development" 379 : 2279-2290, 2012

      12 Leenders M, "Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging" 14 : 585-592, 2013

      13 Peterson MD, "Muscle weakness thresholds for prediction of diabetes in adults" 46 : 619-628, 2016

      14 Li JJ, "Muscle grip strength predicts incident type 2 diabetes : population-based cohort study" 65 : 883-892, 2016

      15 Peterson MD, "Low normalized grip strength is a biomarker for cardiometabolic disease and physical disabilities among U.S. and Chinese adults" 72 : 1525-1531, 2017

      16 Mainous AG 3rd, "Low grip strength and prediabetes in normal-weight adults" 29 : 280-282, 2016

      17 Syddall H, "Is grip strength a useful single marker of frailty?" 32 : 650-656, 2003

      18 Phielix E, "High oxidative capacity due to chronic exercise training attenuates lipid-induced insulin resistance" 61 : 2472-2478, 2012

      19 Di Monaco M, "Handgrip strength is an independent predictor of distal radius bone mineral density in postmenopausal women" 19 : 473-476, 2000

      20 Gale CR, "Grip strength, body composition, and mortality" 36 : 228-235, 2007

      21 Wander PL, "Greater hand-grip strength predicts a lower risk of developing type 2 diabetes over 10 years in leaner Japanese Americans" 92 : 261-264, 2011

      22 Geer EB, "Gender differences in insulin resistance, body composition, and energy balance" 6 (6): 60-75, 2009

      23 Loprinzi PD, "Evidence of a link between grip strength and type 2 diabetes prevalence and severity among a national sample of U.S. adults" 13 : 558-561, 2016

      24 Korean Diabetes Association, "Diabetes fact sheet in Korea 2018" Korean Diabetes Association

      25 Pradhan AD, "C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus" 286 : 327-334, 2001

      26 Lawman HG, "Associations of relative handgrip strength and cardiovascular disease biomarkers in U.S. adults, 2011-2012" 50 : 677-683, 2016

      27 Huang Y, "Association between prediabetes and risk of cardiovascular disease and all cause mortality : systematic review and meta-analysis" 355 : i5953-, 2016

      28 Lee MR, "Association between muscle strength and type 2 diabetes mellitus in adults in Korea : data from the Korea national health and nutrition examination survey(KNHANES)VI" 97 : e10984-, 2018

      29 Ntuk UE, "Association between grip strength and diabetes prevalence in black, South-Asian, and white European ethnic groups : a cross-sectional analysis of 418 656participants in the UK Biobank study" 34 : 1120-1128, 2017

      30 최은영, "20세 이상 한국인에서 상대 악력과 제2형 당뇨병과의 관련성" 대한임상건강증진학회 19 (19): 77-83, 2019

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