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KISSAdhesion to the human gut epithelium is essential for the beneficial effects of probiotics. A human organoid-derived intestinal epithelial cell (IEC) monolayer model recapitulateskey features of the gut epithelium and overcomes limitations of three-di...
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RISS 인기검색어
Lactobacillus gasseri BNR17 Exhibits Superior Adhesion in a Human Intestinal Organoid-Derived Model
한글로보기https://www.riss.kr/link?id=A110105371
-
저자
Ji-Hyun Yun (-) ; Chang Won Ahn (-) ; Yu Mi Jo (-)
- 발행기관
- 학술지명
- 권호사항
-
발행연도
2025
-
작성언어
English
- 주제어
-
등재정보
KCI등재
-
자료형태
학술저널
-
수록면
1-10(10쪽)
- DOI식별코드
- 제공처
-
0
상세조회 -
0
다운로드
부가정보
다국어 초록 (Multilingual Abstract)
Adhesion to the human gut epithelium is essential for the beneficial effects of probiotics.
A human organoid-derived intestinal epithelial cell (IEC) monolayer model recapitulateskey features of the gut epithelium and overcomes limitations of three-dimensionalcultures, providing a suitable platform for assessing bacterial adhesion. In this study, weevaluated the adhesion capacity of the probiotic strain Lactobacillus gasseri BNR17 to humanIECs using fluorescence-based analysis and colony-forming unit assays. BNR17 retainedhigh fluorescence intensity after washing and exhibited approximately 20-fold greaterviable adhesion than the control strain Limosilactobacillus fermentum ACE21. These resultsdemonstrate the strong adhesive capacity of L. gasseri BNR17, supporting its potential foreffective gut colonization and health promotion.
A human organoid-derived intestinal epithelial cell (IEC) monolayer model recapitulateskey features of the gut epithelium and overcomes limitations of three-dimensionalcultures, providing a suitable platform for assessing bacterial adhesion. In this study, weevaluated the adhesion capacity of the probiotic strain Lactobacillus gasseri BNR17 to humanIECs using fluorescence-based analysis and colony-forming unit assays. BNR17 retainedhigh fluorescence intensity after washing and exhibited approximately 20-fold greaterviable adhesion than the control strain Limosilactobacillus fermentum ACE21. These resultsdemonstrate the strong adhesive capacity of L. gasseri BNR17, supporting its potential foreffective gut colonization and health promotion.
Adhesion to the human gut epithelium is essential for the beneficial effects of probiotics.
A human organoid-derived intestinal epithelial cell (IEC) monolayer model recapitulateskey features of the gut epithelium and overcomes limitations of three-dimensionalcultures, providing a suitable platform for assessing bacterial adhesion. In this study, weevaluated the adhesion capacity of the probiotic strain Lactobacillus gasseri BNR17 to humanIECs using fluorescence-based analysis and colony-forming unit assays. BNR17 retainedhigh fluorescence intensity after washing and exhibited approximately 20-fold greaterviable adhesion than the control strain Limosilactobacillus fermentum ACE21. These resultsdemonstrate the strong adhesive capacity of L. gasseri BNR17, supporting its potential foreffective gut colonization and health promotion.
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