Forbes and Albright described the amenorrhea-gaactorrhea syndrome associated with pituitary tumor in 1954. However, only since 1971, with the development of the sens- itⅳe and specific radioimmunoassay for the prolactin by Hwang et al, it has been d...
Forbes and Albright described the amenorrhea-gaactorrhea syndrome associated with pituitary tumor in 1954. However, only since 1971, with the development of the sens- itⅳe and specific radioimmunoassay for the prolactin by Hwang et al, it has been demo- nstrated that high percentages of these tumors are associated with the hyperprolactin- emia. Authors experienced four cases of the pituitary adenoma associated with hyperprola- ctinemia, secondary amenorrhea and galactorrhea and presented them with a brief reⅵew of literatures.