In order to know the effect of thyroid hormone on the iron metabolism, serum ferritin levels obtained by the radioimmunoassay technique were analysed in 12 normal subjects(male : 5, female : 7), 15 hyperthyroid Graves' disease (male: 7, female: 8), 13...
In order to know the effect of thyroid hormone on the iron metabolism, serum ferritin levels obtained by the radioimmunoassay technique were analysed in 12 normal subjects(male : 5, female : 7), 15 hyperthyroid Graves' disease (male: 7, female: 8), 13 euthyroid Graves' disease (male : 4, female: 9) and 9 hypothyroid patients(female: 9)
The results were as follows;
1. The serum ferritin levels of hyperthyroid patients were 96±88.2ng/ml in male and 68.6±41.2ng/ml in female and there was no significant difference compared with those of normal subjects.
2. The serum ferritin levels of euthyroid female patients and hypothyroid female patients were 27.5±14.9ng/ml and 23.5±17.5ng/ml respectively, with were significantly lower than that of hyperthyroid female patients (p<0.01)
3. There was significant correlation between serum T_4 and serum ferritin levels in all female patients(r=0.55, p<0.01).