임상 거체에서 분리된 Enterococcus faecalis와 Enterococcus faecium의 최근 3년간 항균제 내성 추이 = Trends of Antimicrobial Resistance of Enterococcus faecalis and Enterococcus faecium from Clinical Specimens between 2005~2007

다국어 초록 (Multilingual Abstract)

Being predominantly inhabitants of gastrointestinal tract in human, enterococci are opportunistic pathogens of infections that causes UTI, wound infection, septicemia and endorcarditis. Enterococci are not only the etiologic agents of most hospital acquired infections with increasing frequency, but also resistant to many antimicrobial agents at the same time. In this study, the trends of antimicrobial resistance for E. faecalis and E. faecium isolated from clinical specimens at Soonchunhyang University Cheonan Hospital between 2005 and 2007 were determined. Susceptibility were tested by disk diffusion using CLSI guideline and criteria. The percentage of gentamicin high-level resistant isolates of E. faecalis were 54% in 2006 and 65% in 2007 but a higher level of resistance to that gentamicin was found among E. faecium as it was 83% in 2006 and 73% in 2007 respectively. The high-leve1 resistance rates to streptomycin were also increased in 2006 and 2007 from 19% to 24% in E. faecalis and 25% to 31% in E. faecium. Resistance rates to ciprofloxacin in E. faecalis increased significantly in the year 2005 to 2007 from 28% to 42% but these resistance rates were more than 90% in cases of E. faecium isolates. Virtually all of E. faecalis were susceptible to vancomycin, but E. faecium isolates were found resistant to some extent like 16% in 2005, 21% in 2006 and 23% in 2007 respectively. From these findings it was evident that the resistance to many antimicrobial agents are increasing in both E. faecalis and E. faecium isolated from clinical specimens.