한국인집단의 Tetrameric Microsatellites 에서 Y 염색체의 이질성 = Regular Y Chromosomal Heterogeneity of Six Tetrameric Microsatellites in a Korean Population

다국어 초록 (Multilingual Abstract)

Genetic polymorphism of a Korean male population and its relationship to Northeast Asian populations were examined using six tetranucleotide STRs (DYS19, DYS389I, DYS389II, DYS390, DYS391, and DYS393) and one bimorphic marker (DYS287) of the Y chromosome. This work revealed high polymorphism in Korean males, although koreans are known fairly homeogenous because they migrated largely from northeast Asia. The gene diversities of the STR loci ranged form 0.340 to 0.760 with an average of 0.589. The 7 loci produced 45 distinct haplotypes form 57 individuals. Futhermore, the heterogeneity of the haplotypes within clans was observed. These results also led the markers to be useful sources for the paternity test and personal identification in forensic studies for Koreans. When comparing genetic distances between the Korean population and other northeast Asia populations, the allele frequencies of Korean males were quite similar to those of the Chinese population. The similarity between Koreans and Chinese was consistent with the previous findings of Y chromosomal DNAs, but no with those of autosomal DNAs.