Interval from Prostate Biopsy to Radical Prostatectomy Does Not Affect Immediate Operative Outcomes for Open or Minimally Invasive Approach

다국어 초록 (Multilingual Abstract)

Traditionally, urologists recommend an interval of at least 4 weeks after prostate biopsybefore radical prostatectomy. The aim of our study was to evaluate whether the intervalfrom prostate biopsy to radical prostatectomy affects immediate operative outcomes, witha focus on differences in surgical approach. The study population of 1,848 radicalprostatectomy patients was divided into two groups according to the surgical approach:open or minimally invasive. Open group included perineal and retropubic approach, andminimally invasive group included laparoscopic and robotic approach. The cut-off of thebiopsy-to-surgery interval was 4 weeks. Positive surgical margin status, operative time andestimated blood loss were evaluated as endpoint parameters. In the open group, therewere significant differences in operative time and estimated blood loss between the< 4-week and ≥ 4-week interval subgroups, but there was no difference in positivemargin rate. In the minimally invasive group, there were no differences in the threeoutcome parameters between the two subgroups. Multivariate analysis revealed that thebiopsy-to-surgery interval was not a significant factor affecting immediate operativeoutcomes in both open and minimally invasive groups, with the exception of the interval< 4 weeks as a significant factor decreasing operative time in the minimally invasive group.

In conclusion, performing open or minimally invasive radical prostatectomy within 4 weeksof prostate biopsy is feasible for both approaches, and is even beneficial for minimallyinvasive radical prostatectomy to reduce operative time.

참고문헌 (Reference)

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