The purpose of this study is to investigate the thyroid function in mood disorders. The levels of T_3, T_4, TSH were measured in normal conrol(n=16) and mood disorders(n=81) who divided into 3 different diagnostic subgroups by DSM-III-R criteria : maj...
The purpose of this study is to investigate the thyroid function in mood disorders. The levels of T_3, T_4, TSH were measured in normal conrol(n=16) and mood disorders(n=81) who divided into 3 different diagnostic subgroups by DSM-III-R criteria : major depression (n = 29), bipolar depression(n=5) bipolar mania(n = 47).
The results were as follows.
1. The mean serum level of T_4 in mood disorders(n = 81) was significantly lower than that of normal control group (n = 16) (P<0.05).
2. When major depression (n=29), bipolar depression (n=5), bipolar mania(n=47), and normal control(n=16) were compared each other, the mean serul level of T_4 in bipolar depression was significantly lower than that of normal control group(P<0.05).
3. There was no significant difference in mean serum levels of T_3 T_4, and TSH between depressive patients(n=34) and manic patients.