풀망둑(Acanthogobius hasta) liver-specific 동위효소와 eye-specific 젖산탈수소효소 동위효소의 동시 발현 = Coexpresssion of liver-specific and eye-specific lactate dehydrogenase isozymes in Acanthogobius hasta

다국어 초록 (Multilingual Abstract)

A cathodal liver-specific and anodal eye-specific lactate dehydrogenase(EC 1.1.1.27, LDH) isozymes are coexpressed in tissues of Acanthogobius hasta. The activities of LDH were higher in tissues taken from July than from October and it was especially higher in breast muscle. The A₄ isozyme was expressed in skeletal muscle and breast muscle. And the B₄ isozyme was expressed in heart. The liver-specific C₄ isozyme showed lower activity in liver and eye-specific C₄ isozyme showed higher activity in eye tissue. Relative activity(%) of A₄ isozyme was increased and that of C₄ isozyme was decreased in liver taken from July. Therefore C₄ isozyme was played role as lactate oxidase. As a result, Acanthogobius hasta acclimated to hypoxic environment by anaerobic metabolism of LDH isozymes.