직업성 경견완장애 진단시 생화학적 지표의 이용가능성 = Availability of the Biochemical Indicators in the Diagnosis of Occupational Cervicobrachial Disorders

다국어 초록 (Multilingual Abstract)

The increased incidence of occupational cervicobrachial disorder appears to be due to new technology, such as advanced automation and mechanization. That requested for worker's repetitive movements, which were limited to use upper extremities of body. Consequently, increased rate of work concentrated locally on an individual's musculoskeletal system that results in occupational cervicobrachial disorder.
Though the occupational cervicobrachial disorders have been diagnosed by evaluating questionnares from the workers, objective and clear diagnostic criteria were not established.
We tried to develope biochemical indicators that can be used in the dignosis and screening test of the occupational cervicobrachial disorders. The subjects who engaged in the shoemaker factory were divided into 3 groups by their workload; heavy(58 persons), repetitive(55 persons), and control workers(60 persons). The questionnare test was followed by biochemical examinations analyzing blood sample of the subjects. The biochemical indicators used were creatine kinase(CK), aspartate aminotransferase(AST), potassium, lactate, ammonia, uric acid, hypoxanthine, and malondialdehyde(MDA). The concentration of plasma MDA was highest in the heavy workers and there was statistically significant differences in the scores of the questionnare between the workers having concentrations within normal range and above normal range. Also, the levels of serum lactate, plasma uric acid and hypoxanthine were higher in heavy and repetitive workers than control, but, there were not any significant relationships among the groups in questionnare study.
We concluded that these results would be applicable after more study on the standardized method in the analysis of the biochemical indicators and related other clinical tests.