나병 피부 병변의 면역조직화학 염색 - 리소짐 및 S - 100 단백 염색상에 대한 연구 - = Immunohistochemical Staining in Leprosy : Distribution of Lysozyme and S - 100 Protein나병 피부 병변의 면역조직화학 염색 - 리소짐 및 S - 100 단백 염색상에 대한 연구 -

다국어 초록 (Multilingual Abstract)

Immunohistochemical staining was performed in 20 skin granulomas of 16 patients with leprosy using antisera against lysozyme and S-100 protein. In lepromatous leprosy, lysozyme positive cells and S-100 protein positive cells were rarely found in the dermis. However, the histoid leprosy specimen had large numbers of lysozyrne positive cells and S-100 protein positive cells in granuloma. In borderline group, lysozyme positive cells and S-l00 protein positive cells were found in the dermis. S- 100 protein positive cells were diffusely distributed throughuut the granuloma in borderline lepromatous leprosy, while they were often found in lymphocytic mantle in borderline tuberculoid leprosy. In tuberculoid leprosy, lysozymal staining was encouritered in epitheloid cells and giant cells, but S-100 protein positive cells were predominantly found encircling granuloma. In the epidermis, great numbers of S- l00 protein positive cells were found in tuberculoid leprosy than in lepromatous leprosy.