Antioxidant Activity of Maillard Reaction Products Derived from Aqueous and Ethanolic Glucose-Glycine and Its Oligomer Solutions

다국어 초록 (Multilingual Abstract)

The purpose of this study was to evaluate the antioxidant activity of Maillard reaction products (MRPs)in both aqueous and ethanolic glucose-glycine oligomer solutions. The reduction in pH was higher in aqueous MRP solutions than ethanolic MRP solutions. The samples in ethanolic MRP solutions had greater Abs294 nm and Abs420 nm than those in aqueous MRP solutions. The ferrous ion chelating activity of all MRP samples was much higher than the cupric ion chelating ability in both aqueous and ethanolic solutions. The antioxidant activity in ethanolic MRP solutions was higher than that in aqueous MRP solutions. MRPs derived from the diglycine were found to be effective antioxidants in different in vitro assays with regard to the ABTS and DPPH radical scavenging activities,and ferric reducing/antioxidant power.

참고문헌 (Reference)

1 Benzie IFF, "The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: The FRAP assay" 239 : 70-76, 1996

2 Hofmann T, "Studies on the relationship between Mw and the color potency of fractions obtained by thermal treatment of glucose/amino acid and glucose/protein solutions by using ultracentrifugation and color dilution techniques" 46 : 3891-3895, 1998

3 Chuyen NV, "Studies on the reaction of dipeptides with glyoxal" 37 : 327-334, 1973

4 Yamaguchi N, "Studies on antioxidative activities of amino compounds on fats and oils. Part II. Antioxidative activities of dipeptides and their synergistic effects on tocopherol" 22 : 425-430, 1975

5 Ogura K, "Spectroelectrochemical and EQCM studies on the oxidation of glycil-peptides in alkaline medium" 482 : 32-39, 2000

6 Oh YC, "Some volatiles compounds formed from thermal interaction of glucose with glycine, diglycine, triglycine, and tetraglycine" 39 : 1553-1554, 1991

7 Mori N, "Sequence-dependent reactivity of model peptides with glyceraldehydes" 189 : 49-63, 1989

8 De Kok PMT, "Reactivity of peptides in Maillard reaction, In Thermally Generated Flavors: Maillard, Microwave, and Extrusion Processes" American Chemical Society 158-179, 1994

9 Stadtman ER, "Protein oxidation" 899 : 191-208, 2000

10 Buera MDP, "Nonenzymatic browning in liquid model systems of high water activity: Kinetics of color changes due to reaction between glucose and glycine peptides" 52 : 1059-1062, 1987

11 Reynols TM, "Non-enzymatic browning. Sugar-amine interaction, In Carbohydrates and Their Roles" AVI Pub. Co. 219-, 1969

12 O’Brien JO, "Metal ion complexation by products of the Maillard reaction" 58 : 17-27, 1997

13 Seifert ST, "Metal complexation by the peptide-bound Maillard reaction products N(ε)-fructoselysine and N(ε)-carboxymethyllysine" 52 : 2347-2350, 2004

14 Wijewickreme AN, "Metal chelating and antioxidant activity of model Maillard reaction products" 36 : 543-553, 1998

15 Alfawaz M, "Maillard reaction products as antioxidants in precooked ground beef" 51 : 311-318, 1994

16 Shen SC, "Maillard browning in ethanolic solutions" 69 : 273-279, 2004

17 Baltes W, "Investigations on model systems of Maillard reactions" 5 : 137-145, 1981

18 Wang L, "Inhibition of lipid oxidation in cooked beef patties by hydrolyzed potato protein is related to its reducing and radical scavenging ability" 53 : 9186-9192, 2005

19 Rufián-Henares JA, "Functional properties of melanoidins: In vitro antioxidant, antimicrobial, and antihypertensive activities" 40 : 995-1002, 2007

20 Morales FJ, "Free radical scavenging capacity of Maillard reaction products as related to colour and fluorescence" 72 : 119-125, 2001

21 Wu HC, "Free amino acids and peptides as related to antioxidant properties in protein hydrolysates of mackerel (Scomber austriasicus)" 36 : 949-957, 2003

22 Ledl F, "Formation of colored β-pyranones from pentoses and hexoses" 177 : 352-355, 1983

23 Ledl F, "Formation of colored compounds from hexoses" 175 : 262-265, 1982

24 Hartman R, "Food-derived peptides with biological activity: From research to food applications" 18 : 163-169, 2007

25 Lu CY, "Effects of water content on volatile generation and peptide degradation in the Maillard reaction of glycine, diglycine, and triglycine" 53 : 6443-6447, 2005

26 Delgado-Andrade C, "Bioavailability of iron from a heat treated glucose-lysine model food system: Assays in rats and in Caco-2 cells" 84 : 1507-1513, 2004

27 Yen GC, "Antioxidative activity and scavenging effects on xylose-lysine Maillard reaction products" 67 : 415-420, 1995

28 Anese M, "Antioxidant properties of tomato juice as affected by heating" 79 : 750-754, 1999

29 Chen HM, "Antioxidant properties of histidine-containing peptides designed from peptide fragment found in the digests of a soybean protein" 46 : 49-53, 1998

30 Ruiz-Roca B, "Antioxidant properties and metal chelating activity of glucose-lysine heated mixtures: Relationships with mineral absorption across Caco-2 cell monolayers" 56 : 9056-9063, 2008

31 Kong BH, "Antioxidant activity of zein hydrolysates in a liposome system and the possible mode of action" 54 : 6059-6068, 2006

32 Jing H, "Antioxidant activity of sugar-lysine Maillard reaction products in cell free and cell culture systems" 429 : 154-163, 2004

33 Benjakul S, "Antioxidant activity of Maillard reaction products from a porcine plasma protein-sugar model system" 93 : 189-196, 2005

34 Kim JS, "Antioxidant activity of Maillard reaction products derived from aqueous glucose/glycine, diglycine, and triglycine model systems as a function of heating time" 116 : 227-232, 2009

35 Re R, "Antioxidant activity applying an improved ABTS radical cation decolorization assay" 26 : 1231-1237, 1999

36 Dinis TCP, "Action of phenolic derivatives (acetoaminophen, salycilate, and 5-aminosalycilate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers" 315 : 161-169, 1994

37 Zhou S, "Ability of amino acids, dipeptides, polyamines, and sulfhydryls to quench hexanal, a saturated aldehydic lipid oxidation product" 47 : 1932-1936, 1999

38 Ivanov CP, "A study of the interaction of glycine and its oligohomopeptides with formaldehyde and acetaldehyde under possible primitive earth conditions" 13 : 97-108, 1983