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      KCI등재 SCIE SSCI SCOPUS

      Exposure to Environmental Toxins in Mothers of Children with Autism Spectrum Disorder

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      https://www.riss.kr/link?id=A101615815

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      다국어 초록 (Multilingual Abstract)

      Objective Environmental pollutants, especially environmental toxins (ET), may have the potential to disrupt neurodevelopmental pathways during early brain development. This study was designed to test our hypothesis that mothers with autism spectrum di...

      Objective Environmental pollutants, especially environmental toxins (ET), may have the potential to disrupt neurodevelopmental pathways during early brain development. This study was designed to test our hypothesis that mothers with autism spectrum disorder (ASD) children would have less knowledge about ET and more chance to be exposed to ET than mothers with healthy children (MHC).
      MethodsaaOne hundred and six biologic mothers with ASD children (MASD) and three hundred twenty four biologic mothers with healthy children MHC were assessed using two questionnaires asking about ET.
      ResultsaaThe total score in response to questions related to knowledge about ET in MHC was higher than that in MASD. The possibility of exposure to ET was higher in MASD than MHC.
      MASD showed higher sub-scale scores in terms of exposures to canned food, plastics, waste incinerators, old electronics, microwavable food, and textiles.
      ConclusionaaThe current results show that reduced knowledge about ET and greater exposure to ET may be associated with autism spectrum disorder.

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      참고문헌 (Reference)

      1 류재천, "내분비계 장애물질의 개요와 검색법의 고찰" 한국농약과학회 6 (6): 1-156, 2002

      2 Strosnider H, "Workgroup report: public health strategies for reducing aflatoxin exposure in developing countries" 114 : 1898-1903, 2006

      3 Barnea-Goraly N, "White matter structure in autism: preliminary evidence from diffusion tensor imaging" 55 : 323-326, 2004

      4 Smith JW, "Thyroid hormones, brain function and cognition: a brief review" 26 : 45-60, 2002

      5 Moriyama K, "Thyroid hormone action is disrupted by bisphenol A as an antagonist" 87 : 5185-5190, 2002

      6 Hardy ML, "The toxicology of the three commercial polybrominated diphenyl oxide (ether) flame retardants" 46 : 757-777, 2002

      7 Mariussen E, "The effect of brominated flame retardants on neurotransmitter uptake into rat brain synaptosomes and vesicles" 43 : 533-542, 2003

      8 Schumann CM, "The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages" 24 : 6392-6401, 2004

      9 Lin Y, "Study on bisphenol A induced primary cultured mesencephalic neuronal cell injury by oxidative stress" 35 : 419-422, 2006

      10 Bremmer HJ, "Sources of Dioxins in the Netherlands" Bilthoven 1991

      1 류재천, "내분비계 장애물질의 개요와 검색법의 고찰" 한국농약과학회 6 (6): 1-156, 2002

      2 Strosnider H, "Workgroup report: public health strategies for reducing aflatoxin exposure in developing countries" 114 : 1898-1903, 2006

      3 Barnea-Goraly N, "White matter structure in autism: preliminary evidence from diffusion tensor imaging" 55 : 323-326, 2004

      4 Smith JW, "Thyroid hormones, brain function and cognition: a brief review" 26 : 45-60, 2002

      5 Moriyama K, "Thyroid hormone action is disrupted by bisphenol A as an antagonist" 87 : 5185-5190, 2002

      6 Hardy ML, "The toxicology of the three commercial polybrominated diphenyl oxide (ether) flame retardants" 46 : 757-777, 2002

      7 Mariussen E, "The effect of brominated flame retardants on neurotransmitter uptake into rat brain synaptosomes and vesicles" 43 : 533-542, 2003

      8 Schumann CM, "The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages" 24 : 6392-6401, 2004

      9 Lin Y, "Study on bisphenol A induced primary cultured mesencephalic neuronal cell injury by oxidative stress" 35 : 419-422, 2006

      10 Bremmer HJ, "Sources of Dioxins in the Netherlands" Bilthoven 1991

      11 Harrad S, "Preliminary assessment of U.K. human dietary and inhalation exposure to polybrominated diphenyl ethers" 38 : 2345-2350, 2004

      12 Van Wijnen J, "Placental transport of PCDDs and PCDFs in infants" Eco informa press 1990

      13 Huisman M, "Perinatal exposure to polychlorinated biphenyls and dioxins and its effect on neonatal neurological development" 41 : 111-127, 1995

      14 Kenet T, "Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex" 104 : 7646-7651, 2007

      15 She J, "PBDEs in the San Francisco Bay Area: measurements in harbor seal blubber and human breast adipose tissue" 46 : 697-707, 2002

      16 Davis C, "Oestrogens induce G(1) arrest in benzo[a]pyrene-treated MCF-7 breast cells whilst enhancing genotoxicity and clonogenic survival" 17 : 431-438, 2002

      17 Kodavanti PR, "Neurotoxicity of Persistent Organic Pollutants: Possible Mode(s) of Action and Further Considerations" 3 : 273-305, 2006

      18 Viberg H, "Neonatal exposure to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice" 192 : 95-106, 2003

      19 Viberg H, "Neonatal exposure to decabrominated diphenyl ether (PBDE 209) results in changes in BDNF, CaMKII and GAP-43, biochemical substrates of neuronal survival, growth, and synaptogenesis" 29 : 152-159, 2008

      20 Crawley JN, "Mouse behavioral assays relevant to the symptoms of autism" 17 : 448-459, 2007

      21 Cantor RM, "Molecular genetics of autism" 11 : 137-142, 2009

      22 Achenbach TM, "Manual for the Child Behavior Checklist and Revised Child Behavior Profile" University of Vermont, Department of Psychiatry 1983

      23 Kim KI, "Korean manual of Symptom Checklist-90- Revision" Chung Ang Aptitude 1984

      24 CERHR, "Interm NTP-CERHR report on the reproductive and developmental toxicity of bisphenol A"

      25 Vojdani A, "Infections, toxic chemicals and dietary peptides binding to lymphocyte receptors and tissue enzymes are major instigators of autoimmunity in autism" 16 : 189-199, 2003

      26 Eriksson P, "Exposure to DDT during a defined period in neonatal life induces permanent changes in brain muscarinic receptors and behaviour in adult mice" 582 : 277-281, 1992

      27 Vreugdenhil HJ, "Effects of prenatal PCB and dioxin background exposure on cognitive and motor abilities in Dutch children at school age" 140 : 48-56, 2002

      28 Koopman-Esseboom C, "Effects of polychlorinated biphenyl/ dioxin exposure and feeding type on infants’ mental and psychomotor development" 97 : 700-706, 1996

      29 Vreugdenhil HJ, "Effects of perinatal exposure to PCBs and dioxins on play behavior in Dutch children at school age" 110 : A593-A598, 2002

      30 Kuroda Y, "Effects of endocrine disruptors on brain development. Development of novel assay systems for risk assessment" 10 : 23-33, 2003

      31 Branchi I, "Early developmental exposure to BDE 99 or Aroclor 1254 affects neurobehavioural profile: interference from the administration route" 26 : 183-192, 2005

      32 Kimua-Kuroda J, "Disrupting effects of hydroxypolychlorinated biphenyl (PCB) congeners on neuronal development of cerebellar Purkinje cells: a possible causal factor for developmental brain disorders?" 67 : S412-S420, 2007

      33 Schecter A, "Dioxins, dibenzofurans, dioxin-like PCBs, and DDE in U.S. fast food, 1995" 34 : 1449-1457, 1997

      34 Peterson RE, "Developmental and reproductive toxicity of dioxins and related compounds: cross-species comparisons" 23 : 283-335, 1993

      35 Just MA, "Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity" 127 : 1811-1821, 2004

      36 Kim BH, "Concentrations of polybrominated diphenyl ethers, polychlorinated dibenzo-p-dioxins and dibenzofurans, and polychlorinated biphenyls in human blood samples from Korea" 336 : 45-56, 2005

      37 Chen YC, "Cognitive development of Yu- Cheng (“oil disease”) children prenatally exposed to heat-degraded PCBs" 268 : 3213-3218, 1992

      38 Oh KJ, "Child Behavior Checklist Korean version (KCBCL)" Seoul Central Research Center 1997

      39 Viberg H, "Changes in spontaneous behaviour and altered response to nicotine in the adult rat, after neonatal exposure to the brominated flame retardant, decabrominated diphenyl ether (PBDE 209)" 28 : 136-142, 2007

      40 Courchesne E, "Brain development in autism: early overgrowth followed by premature arrest of growth" 10 : 106-111, 2004

      41 Le HH, "Bisphenol A is released from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons" 176 : 149-156, 2008

      42 Le HH, "Bisphenol A is release from polycarbonate drinking bottles and mimics the neurotoxic actions of estrogen in developing cerebellar neurons" 176 : 149-156, 2008

      43 Bindhumol V, "Bisphenol A induces reactive oxygen species generation in the liver of male rats" 188 : 117-124, 2003

      44 Behnisch PA, "Bioanalytical screening methods for dioxins and dioxin-like compounds a review of bioassay/biomarker technology" 27 : 413-439, 2001

      45 Davisson AN, "Applied neurochemistry" Blackwell 1968

      46 Chang EA, "A comparison of environmental risk perceptions between general public and experts" 16 : 75-84, 2001

      47 Eriksson P, "A brominated flame retardant, 2,2’,4,4’,5-pentabromodiphenyl ether: uptake, retention, and induction of neurobehavioral alterations in mice during a critical phase of neonatal brain development" 67 : 98-103, 2002

      48 Sul D, "2,3,7,8- TCDD neurotoxicity in neuroblastoma cells is caused by increased oxidative stress, intracellular calcium levels, and tau phosphorylation" 255 : 65-71, 2009

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2010-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2009-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2007-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 1.42 0.21 1.07
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.87 0.77 0.51 0.1
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