Methyl Aminolevulinate(MAL)와 Light Emitting Diodes(LEDs)를 이용하여 국소 광역동 요법으로 치료한 여드름 1례 = A Case of Acne Treated by Topical Photodynamic Therapy using with Methyl Aminolevulinate and Light Emitting Diodes

다국어 초록 (Multilingual Abstract)

Ance is a common multifactorial skin disease of the pilosebaceous unit. Conventional treatments of acne include a variety of topical agents (cleansing, antibiotics agents, benzoyl peroxide, retinoids) and oral medications (antibiotics, retinoids, hormones). But there are some disadvantages in terms of adverse effects and patient inconvenience with such treatments. Therefore new effective well-tolerable treatments needed.
Photodynamic therapy (PDT) is a non-invasive therapeutic modality which is developing increasing use in dermatology. Photodynamic therapy (PDT) using with the new highly selective photosensitizer methyl aminolevulinate (MAL)(MetvixⓇ, Galderma, U.K.) is a promising treatment modality for acne.
We report herein a case of acne treated by PDT using with MAL, with satisfactory outcome in clinical aspects.

목차 (Table of Contents)

• 서론
• 증례
• 고찰
• 참고문헌

참고문헌 (Reference)

1 Mirta A MRCP, "Topical photodynamic therapy for non-cancerous skin conditions" 3 (3): 116-127, 2006

2 Siddiqui MA, "Topical methyl aminolevulinate" 5 (5): 127-137, 2004

3 Hörfelt C, "Topical methyl aminolaevulinate photodynamic therapy for treatment of facial acne vulgaris: results of a randomized, controlled study" 155 (155): 608-613, 2006

4 Hong SB, "Topical aminolevulinic acid-photodynamic therapy for the treatment of acne vulgaris" 21 (21): 322-325, 2005

5 Pollock B, "Topical aminolaevulinic acidphotodynamic therapy for the treatment of acne vulgaris: a study of clinical efficacy and mechanism of action" 151 (151): 616-622, 2004

6 Hongcharu W, "Topical ALA-photodynamic therapy for the treatment of acne vulgaris" 115 (115): 183-192, 2000

7 Calzavara-Pinton PG, "Photodynamic therapy: update 2006. Part 2: Clinical results" 21 (21): 439-451, 2007

8 Kennedy JC, "Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience" 6 (6): 143-148, 1990

9 Itoh Y, "Photodynamic therapy of acne vulgaris with topical delta-aminolaevulinic acid and incoherent light in Japanese patients" 144 (144): 575-579, 2001

10 Wiegell SR, "Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid versus methyl aminolevulinate" 54 (54): 647-651, 2006

11 Katsambas AD, "Guidelines for treating acne" 22 (22): 439-444, 2004

12 Morton CA, "Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group" 146 (146): 552-567, 2002

13 Morton CA, "Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group" 146 (146): 552-567, 2002

14 Haedersdal M, "Evidence-based review of lasers, light sources and photodynamic therapy in the treatment of acne vulgaris" 22 (22): 267-278, 2008

15 Dreno B, "Epidemiology of acne" 206 (206): 7-10, 2003

16 Gold MH, "Acne and PDT: new techniques with lasers and light sources" 22 (22): 67-72, 2007

17 Yeung CK, "A comparative study of intense pulsed light alone and its combination with photodynamic therapy for the treatment of facial acne in asian skin" 39 (39): 1-6, 2007