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    Complete genome sequence of Streptomyces sp. MMS22-DDSA8, a soil actinobacterium exhibiting antifungal activity

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    https://www.riss.kr/link?id=A109114070

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    Streptomyces sp. MMS22-DDSA8 is a Gram-positive, aerobic, filamentous and spore-forming actinobacterium isolated from soil. Strain MMS22-DDSA8 exhibited antimicrobial activity against filamentous fungi. In this study, the whole genome sequence of strain MMS22-DDSA8 was determined, and a single contig consisting of 8.22 Mb in length with a G + C content of 71.2% was obtained. The 16S rRNA gene and genome-based analyses indicated that strain MMS22-DDSA8 shared highest similarities with Streptomyces lydicamycinicus NBRC 110027T. The in silico genome analysis indicated presence of 26 biosynthetic gene clusters for secondary metabolite production, including those related to antimicrobial activity. The detailed analysis of genome indicated a high potential of strain MMS22-DDSA8 as a novel producer of antimicrobial compounds.
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    Streptomyces sp. MMS22-DDSA8 is a Gram-positive, aerobic, filamentous and spore-forming actinobacterium isolated from soil. Strain MMS22-DDSA8 exhibited antimicrobial activity against filamentous fungi. In this study, the whole genome sequence of stra...

    Streptomyces sp. MMS22-DDSA8 is a Gram-positive, aerobic, filamentous and spore-forming actinobacterium isolated from soil. Strain MMS22-DDSA8 exhibited antimicrobial activity against filamentous fungi. In this study, the whole genome sequence of strain MMS22-DDSA8 was determined, and a single contig consisting of 8.22 Mb in length with a G + C content of 71.2% was obtained. The 16S rRNA gene and genome-based analyses indicated that strain MMS22-DDSA8 shared highest similarities with Streptomyces lydicamycinicus NBRC 110027T. The in silico genome analysis indicated presence of 26 biosynthetic gene clusters for secondary metabolite production, including those related to antimicrobial activity. The detailed analysis of genome indicated a high potential of strain MMS22-DDSA8 as a novel producer of antimicrobial compounds.

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    참고문헌 (Reference)

    1 Blin K, "antisMASH 7. 0 : New and improved predictions for detection, regulation, chemical structures and visualisation" 51 : W46-W50, 2023

    2 Meier-Kolthoff JP, "TYGS is an automated high-throughput platform for state-of-the-art genome-based taxonomy" 10 : 2182-, 2019

    3 Komaki H, "Streptomyces lydicamycinicus sp. nov. and its secondary metabolite biosynthetic gene clusters for polyketide and nonribosomal peptide compounds" 8 : 370-, 2020

    4 Olanrewaju OS, "Streptomyces : implications and interactions in plant growth promotion" 103 : 1179-1188, 2019

    5 Alam K, "Streptomyces : The biofactory of secondary metabolites" 13 : 968053-, 2022

    6 Walker BJ, "Pilon : an integrated tool for comprehensive microbial variant detection and genome assembly improvement" 9 : e112963-, 2014

    7 Tatusova T, "NCBI prokaryotic genome annotation pipeline" 44 : 6614-6624, 2016

    8 Parte AC, "List of prokaryotic names with standing in nomenclature(LPSN)moves to the DSMZ" 70 : 5607-5612, 2020

    9 Yoon SH, "Introducing EzBioCloud : a taxonomically united database of 16S rRNA gene sequences and whole-genome assemblies" 67 : 1613-1617, 2017

    10 Kämpfer P, "Bergey's Manual of Systematics of Archaea and Bacteria" John Wiley & Sons, Inc 1-414, 2015

    1 Blin K, "antisMASH 7. 0 : New and improved predictions for detection, regulation, chemical structures and visualisation" 51 : W46-W50, 2023

    2 Meier-Kolthoff JP, "TYGS is an automated high-throughput platform for state-of-the-art genome-based taxonomy" 10 : 2182-, 2019

    3 Komaki H, "Streptomyces lydicamycinicus sp. nov. and its secondary metabolite biosynthetic gene clusters for polyketide and nonribosomal peptide compounds" 8 : 370-, 2020

    4 Olanrewaju OS, "Streptomyces : implications and interactions in plant growth promotion" 103 : 1179-1188, 2019

    5 Alam K, "Streptomyces : The biofactory of secondary metabolites" 13 : 968053-, 2022

    6 Walker BJ, "Pilon : an integrated tool for comprehensive microbial variant detection and genome assembly improvement" 9 : e112963-, 2014

    7 Tatusova T, "NCBI prokaryotic genome annotation pipeline" 44 : 6614-6624, 2016

    8 Parte AC, "List of prokaryotic names with standing in nomenclature(LPSN)moves to the DSMZ" 70 : 5607-5612, 2020

    9 Yoon SH, "Introducing EzBioCloud : a taxonomically united database of 16S rRNA gene sequences and whole-genome assemblies" 67 : 1613-1617, 2017

    10 Kämpfer P, "Bergey's Manual of Systematics of Archaea and Bacteria" John Wiley & Sons, Inc 1-414, 2015

    11 Kolmogorov M, "Assembly of long, error-prone reads using repeat graphs" 37 : 540-546, 2019

    12 Pacios-Michelena S, "Application of Streptomyces antimicrobial compounds for the control of phytopathogens" 5 : 696518-, 2021

    13 Suda H, "Antipain, a new protease inhibitor isolated from actinomycetes" 25 : 263-266, 1972

    14 Lee JH, "Antifungal potential of actinobacteria against phytopathogenic fungi" Chungnam National University 2023

    15 Ranjani A, "Actinobacteria - Basics and Biotechnological Applications" Intech Open 1-, 2016

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