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      악성 침샘종양의 세침흡인 세포검사의 정도관리 = Quality Assuarance on Fine Needle Aspiration Cytology of Malignant Salivary Gland Neoplasms

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      https://www.riss.kr/link?id=A101691513

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      다국어 초록 (Multilingual Abstract)

      To evaluate the quality of fine needle aspiration cytology diagnosis on malignant salivary gland neoplasms, cytologic findings were correlated with histologic diagnosis of 56 surgically removed malignant salivary gland tumors. Seven cases (12.5%) were insufficient, 23 cases (41.1%) were diagnosed as malignant, 17 (30.4%) cases were accurately diagnosed by histologic subtype, and 9 cases (16%) were diagnosed as benign. Five out of 9 false negative cases were misdiagnosed as pleomorphic adenomas. Except the cases with insufficient specimen, overall sensitivity was 81.6%, and the sensitivity varied according to the histologic subtype; 91% in salivary duct carcinoma, 100% in carcinoma ex pleomorphic adenoma, 50% in mucoepidermoid carcinoma, 63% in adenoid cystic carcinoma, and 50% in acinic cell carcinoma. The diagnostic accuracy differed among cytopathologists irrespective of periods after acquisition of board of pathologists. These results confirm that salivary gland neoplasm can be easily misdiagnosed in fine needle aspiration cytology and a great caution should be given in diagnosing the benign appearing salivary aspirates to avoid under-diagnosis of malignant neoplasm with low grade cytologic atypia.
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      To evaluate the quality of fine needle aspiration cytology diagnosis on malignant salivary gland neoplasms, cytologic findings were correlated with histologic diagnosis of 56 surgically removed malignant salivary gland tumors. Seven cases (12.5%) were...

      To evaluate the quality of fine needle aspiration cytology diagnosis on malignant salivary gland neoplasms, cytologic findings were correlated with histologic diagnosis of 56 surgically removed malignant salivary gland tumors. Seven cases (12.5%) were insufficient, 23 cases (41.1%) were diagnosed as malignant, 17 (30.4%) cases were accurately diagnosed by histologic subtype, and 9 cases (16%) were diagnosed as benign. Five out of 9 false negative cases were misdiagnosed as pleomorphic adenomas. Except the cases with insufficient specimen, overall sensitivity was 81.6%, and the sensitivity varied according to the histologic subtype; 91% in salivary duct carcinoma, 100% in carcinoma ex pleomorphic adenoma, 50% in mucoepidermoid carcinoma, 63% in adenoid cystic carcinoma, and 50% in acinic cell carcinoma. The diagnostic accuracy differed among cytopathologists irrespective of periods after acquisition of board of pathologists. These results confirm that salivary gland neoplasm can be easily misdiagnosed in fine needle aspiration cytology and a great caution should be given in diagnosing the benign appearing salivary aspirates to avoid under-diagnosis of malignant neoplasm with low grade cytologic atypia.

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      참고문헌 (Reference)

      1 "타액선 종괴에 대한 세침흡인 세포검사의 역할." 57 : 533-540, 1999

      2 "타액관 암종의 임상양상 및 치료결과." 46 : 318-323, 2003

      3 "이태숙. 타액선 질환의 세침흡인 생검에 관한 세포학적 연구. 대한세포병리학회지 1994" 120-29,

      4 "이상국. 타액선 병변의 세침흡인 세포검사. 대한세포병리학회지 1993" 111-20,

      5 "이동화. 타액선의 세침흡인 세포검사. -221예 분석-" 10 : 133-143, 1999

      6 "선양낭포성암 및 점액표피암의 세침흡인 세포학적 감별. 대한세포병리학회지 1990" 60-7,

      7 "두경부 질환. In : 대한병리학회 발행. 병리학," 고문사 494-516, 2003

      8 "The salivary gland. In: Gray W, McKee GT. Diagnostic cytopathology." Churchil Livingstone. 305-323, 2002

      9 "Salivary gland. In: Ramzy I. Clinical cytopathology and aspiration biopsy." McGrawHill. 389-408, 2000

      10 "Salivary and lacrimal gland. In: Gnepp DR. Diagnostic surgical pathology of the head and neck." Saunders Co. 325-430, 2001

      1 "타액선 종괴에 대한 세침흡인 세포검사의 역할." 57 : 533-540, 1999

      2 "타액관 암종의 임상양상 및 치료결과." 46 : 318-323, 2003

      3 "이태숙. 타액선 질환의 세침흡인 생검에 관한 세포학적 연구. 대한세포병리학회지 1994" 120-29,

      4 "이상국. 타액선 병변의 세침흡인 세포검사. 대한세포병리학회지 1993" 111-20,

      5 "이동화. 타액선의 세침흡인 세포검사. -221예 분석-" 10 : 133-143, 1999

      6 "선양낭포성암 및 점액표피암의 세침흡인 세포학적 감별. 대한세포병리학회지 1990" 60-7,

      7 "두경부 질환. In : 대한병리학회 발행. 병리학," 고문사 494-516, 2003

      8 "The salivary gland. In: Gray W, McKee GT. Diagnostic cytopathology." Churchil Livingstone. 305-323, 2002

      9 "Salivary gland. In: Ramzy I. Clinical cytopathology and aspiration biopsy." McGrawHill. 389-408, 2000

      10 "Salivary and lacrimal gland. In: Gnepp DR. Diagnostic surgical pathology of the head and neck." Saunders Co. 325-430, 2001

      11 "Frozen section during parotid surgery revisited: efficacy of its applications and changing trend of indications" 24 : 191-197, 2002

      12 Lurie M,, "Diagnostic value of fine-needle aspiration from parotid gland lesions." 4 : 681-683, 2002

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      연월일 이력구분 이력상세 등재구분
      2009-01-01 평가 학술지 폐간(기타)
      2007-01-01 평가 등재후보학술지 유지(등재후보1차) KCI등재후보
      2005-01-01 평가 등재후보학술지 선정(신규평가) KCI등재후보
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