Receptor activation by antigens, cytokines, hormones, and growth factors

목차 (Table of Contents)

• CONTENTS
• Preface. / By DAVID NAOR ; PIERRE DE MEYTS = xiii
• Part I. Receptor Structures and Signaling Mechanisms Common to Multiple Biological Systems
• Definition of Signals for Neuronal Differentiation. / By AXEL OBERMEIER ; RALPH A. BRADSHAW ; KLAUS SEEDORF ; AXEL CHOIDAS ; JOSEPH SCHLESSINGER ; AXEL ULLRICH = 1
• Structure and Catalytic Properties of Protein Tyrosine Phosphatases. / By JACK E. DIXON = 18
• The G Protein-coupled Receptor Family and One of Its Members, the TSH Receptor. / By G. VASSART ; F. DESARNAUD ; L. DUPREZ ; D. EGGERICKX ; O. LABB$$\acute E$$ ; F. LIBERT ; C. MOLLEREAU ; J. PARMA ; R. PASCHKE ; M. TONACCHERA ; P. VANDERHAEGHEN ; J. VAN SANDE ; J. DUMONT ; M. PARMENTIER = 23
• Inositol Trisphosphate and Calcium Signaling. / By MICHAEL J. BERRIDGE = 31
• Interaction of Signaling and Trafficking Proteins with the Carboxyterminus of the Epidermal Growth Factor Receptor. / By GRAHAM CARPENTER ; CONCEPCI$$\acute O$$ SOLER ; JOSEP BAULIDA ; LAURA BEGUINOT ; ALEXANDER SORKIN = 44
• Part II. Cell Receptors of the Immune System: Development, Structure, Function, and Diversity
• Control of T-Cell Development by the Pre-T and $$\alpha$$$$\beta$$ T-Cell Receptor. / By HARALD VON BOEHMER = 52
• T-Cell Recognition of Antigen: A Process Controlled by Transient Intermolecular Interactions. / By J. JAY BONIFACE ; MARK M. DAVIS = 62
• Receptors That Regulate T-Cell Susceptibility to Apoptotic Cell Death. / By LAWRENCE H. BOISE ; ANDY J. MINN ; CRAIG B. THOMPSON = 70
• Signaling Difference between Class IgM and IgD Antigen Receptors. / By KWANG-MYONG KIM ; MICHAEL RETH = 81
• Interaction of p5$$6^{lck}$$ with CD4 in the Yeast Two-hybrid System. / By KERRY S. CAMPBELL ; ANNIE BUDER ; ULRICH DEUSCHLE = 89
• Induction of Terminal Differentiation of Promyelocytic HL-60 Leukemic Cells Implanted with Lymphocyte Receptors and Stimulated with Various Lymphocyte Stimulators. / By IRIT ALTBOUM ; ISRAEL ZAN-BAR = 93
• Independent Signaling for Growth Arrest and Apoptosis by Ig$$\alpha$$ and Ig$$\beta$$ Subunits of the B-Cell Antigen Receptor Complex. / By XIAO-RUI YAO ; DAVID W. SCOTT = 96
• Part III. Signal Transduction and Second Messengers in Activated Cells of the Immune System
• The Kinase-dependent Function of Lck in T-Cell Activation Requires an Intact Site for Tyrosine Autophosphorylation. / By HUA Xu ; DAN R. LITTMAN = 99
• Coreceptors and Adapter Proteins in T-Cell Signaling. / By K. S. RAVICHANDRAN ; J. C. PRATT ; S. SAWASDIKOSOL ; H. Y. IRIE ; S. J. BURAKOFF = 117
• Symmetry of the Activation of Cyclin-dependent Kinases in Mitogen and Growth Factor-stimulated T Lymphocytes. / By JAIME F. MODIANO ; JOANNE DOMENICO ; AGOTA SZEPESI ; NAOHIRO TERADA ; JOSEPH J. LUCAS ; ERWIN W. GELFAND = 134
• Molecular and Genetic Insights into T-Cell Antigen Receptor Signaling. / By ARTHUR WEISS ; THERESA KADLECEK ; MAKIO IWASHIMA ; ANDREW CHAN ; NICOLAI VAN OERS = 149
• Signal Transduction Mediated by the T-Cell Antigen Receptor. / By LAWRENCE E. SAMELSON ; JERALD A. DONOVAN ; NOAH ISAKOV ; YASUO OTA ; RONALD L. WANGE = 157
• Genetic Dissection of the Transducing Subunits of the T-CelI Antigen Receptor. / By BERNARD MALISSEN ; GRACE Ku ; MIRJAM HERMANS ; ERIC VIVIER ; MARIE MALISSEN = 173
• The Cyclosporin-sensitive Transcription Factor NFATp Is Expressed in Several Classes of Cells in the Immune System. / By DON Z. WANG ; PATRICIA G. MCCAFFREY ; ANJANA RAO = 182
• Signal Transduction by the B-CelI Antigen Receptor. / By ANTHONY L. DEFRANCO ; JAMES D. RICHARDS ; JONATHAN H. BLUM ; TRACY L. STEVENS ; DEBBIE A. LAW ; VIVIEN W.-F. CHAN ; SANDIP K. DATTA ; SHAUN P. FOY ; SHARON L. HOURIHANE ; MICHAEL R. GOLD ; LINDA MATSUUCHI = 195
• Interaction of Shc with Grb2 Regulates the Grb2 Associadon with mSOS. / By K. S. RAVICHANDRAN ; U. LORENZ ; S. E. SHOELSON ; S. J. BURAKOFF = 202
• A 115 kDa Tyrosine Phosphorylated Protein Associates with Grb-2 in Activated Jurkat Cells. / By HERMAN MEISNER ; MICHAEL P. CZECH = 204
• Csk Associates with the TCR $$\zeta$$ and $$\epsilon$$ Chains through Its SH2 Domain. / By THORUNN RAFNAR ; JONATHAN P. SCHNECK ; MARY E. BRUMMET ; DAVID G. MARSH ; BRANIMIR $$\check C$$ATIPOVI$$\acute C$$ = 206
• Fc Receptor Stimulation of PI 3-Kinase in NK Cells Is Associated with Protein Kinase C-independent Granule Release and Cell-mediated Cytotoxicity. / By JOY D. BONNEMA ; LARRY M. KARNITZ ; RENEE A. SCHOON ; ROBERT T. ABRAHAM ; PAUL J. LEIBSON = 209
• Potentiation of B-Cell Antigen Receptor-mediated Signal Transduction by the Heterologous src Family Protein Tyrosine Kinase, src. / By JIEJIAN LIN ; ANNE L. BURKHARDT ; JOSEPH B. BOLEN ; LOUIS B. JUSTEMENT = 214
• Regulation of Human Natural Killer-Cell Lytic Activity by Serine／Threonine Phosphatases and Kinases. / By ANIL BAJPAI ; ZACHARIE BRAHMI = 216
• Mechanisms of Enhanced Nuclear Translocation of the Transcription Factors c-Rel and NF-kB by CD28 Costimulation in Human T Lymphocytes. / By JENN-HAUNG LAI ; GY$$\ddot O$$RGYI HORVATH ; YONGQIN Li ; TSE-HUA TAN = 220
• Part IV. Cytokine Receptors
• Cytokine Signal Transduction through a Homo- or Heterodimer of gpl30. / By TADAMITSU KISHIMOTO ; TAKASHI TANAKA ; KANJI YOSHIDA ; SHIZUO AKIRA ; TETSUYA TAGA = 224
• IL-2 Signaling Involves Recruitment and Activation of Multiple Protein Tyrosine Kinases by the IL-2 Receptor. / By TADATSUGU TANIGUCHI ; TADAAKI MIYAZAKI ; YASUHIRO MINAMI ; ATSUO KAWAHARA ; HODAKA FUJII ; YOKO NAKAGAWA ; MASANORI HATAKEYAMA ; ZHAO-JUN Liu = 235
• Costimulation Requirement for AP-1 and NF-KB Transcription Factor Activation in T Cells. / By STEFFEN JUNG ; AVRAHAM YARON ; IRIT ALKALAY ; ADA HATZUBAI ; AYELET AVRAHAM ; YINON BEN-NERIAH = 245
• Stmctural Aspects of Cytokine／Receptor Interactions. / By Nicos A. NICOLA = 253
• Cell Growth Signal Transduction Is Quantal. / By KENDALL A. SMITH = 263
• TNFa Is an Effective Therapeutic Target for Rheumatoid Arthritis. / By MARC FELDMANN ; FIONULA M. BRENNAN ; MICHAEL J. ELLIOTT ; RICHARD O. WILLIAMS ; RAVINDER N. MAINI = 272
• Investigation of Ligand Binding to Members of the Cytokine Receptor Family within a Microbial System. / By K. H. YOUNG ; B. A. OZENBERGER = 279
• The Proline-rich Motif Is Necessary but Not Sufficient for Prolactin Receptor Signal Transduction. / By KEVIN D. O'NEAL ; LI-YUAN YU-LEE ; WILLIAM T. SHEARER = 282
• Activation of Multiple Protein Kinases by Interleukin-1. / By J. E. DUNFORD ; N. R. CORBETT ; C. L. VARLEY ; C. H. DAWSON ; B. L. BROWN ; P. R. M. DOBSON = 285
• IL-8 Signal Transduction in Human Neutrophils. / By CINDY KNALL ; G. SCOTT WORTHEN ; ANNE METTE BUHL ; GARY L. JOHNSON = 288
• IL-8 Induces Calcium Mobilization in Interleukin-2-activated Natural Killer Cells Independently of Inositol 1,4,5 Trisphosphate. / By ALA AL-AOUKATY ; ADEL GIAID ; AZZAM A. MAGHAZACHI = 292
• Interleukin-11 Induces Tyrosine Phosphorylation, and c-jun and c-fos mRNA Expression in Human K562 and U937 Cells. / By SAMUEL E. ADUNYAH ; GLENDORA C. SPENCER ; ROLAND S. COOPER ; JUAN A. RIVERO ; KARAMBA CEESAY = 296
• Analysis of the Interaction between Two TGF-$$\beta$$-binding Proteins and Three TGF-$$\beta$$ Isofonns Using Surface PIasmon Resonance. / By M. D. O'CoNNOR-McCoURT ; P. SEGARINI ; S. GROTHE ; M. L.-S. TSANG ; J. A. WEATHERBEE = 300
• Part V. Growth Factor and Hormone Receptors: Structure and Function
• The Stress-activated Protein Kinases: A Novel ERK Subfamily Responsive to Cellular Stress and Inflammatory Cytokines. / By JOHN M. KYRIAKIS ; JAMES R. WOODGETT ; JOSEPH AVRUCH = 303
• Protein Serine／Threonine Kinases of the MAPK Cascade. / By J. D. GRAVES ; J. S. CAMPBELL ; E. G. KREBS = 320
• Structural Aspects of Receptor Dimerization: c-Kit as an Example. / By JANNA M. BLECHMAN ; YOSEF YARDEN = 344
• Signal Transduction Interception as a Novel Approach to Disease Management. / By ALEXANDER LEVITZKI = 363
• Common and Distinct Elements in Insulin and PDGF Signaling. / By MARTIN G. MYERS JR. ; BENTLEY CHEATHAM ; TRACEY L. FISHER ; BOZENA R. JACHNA ; C. RONALD KAHN ; JONATHAN M. BACKER ; MORRIS F. WHITE = 369
• Mechanism of Insulin and IGF-I Receptor Activation and Signal Transduction Specificity: Receptor Dimer Cross-linking, Bell-shaped Curves, and Sustained versus Transient Signaling. / By PIERRE DE MEYTS ; BIRGITTE URS$$\phi$$ ; CLAUS T. CHRISTOFFERSEN ; RONALD M. SHYMKO = 388
• The Role of the Insulin-like Growth Factor-I Receptor in Cancer. / By D. LEROITH ; H. WERNER ; S. NEUENSCHWANDER ; T. KALEBIC ; L. J. HELMAN = 402
• Mitogenic Potential of Insulin on Lymphoma Cells Lacking IGF-1 Receptor. / By DVORAK ISH-SHALOM ; GURI TZIVION ; CLAUS T. CHRISTOFFERSEN ; BIRGITTE URS$$\phi$$ ; PIERRE DE MEYTS ; DAVID NAOR = 409
• Platelet-derived Growth Factor: Distinct Signal Transduction Pathways Associated with Migration versus Proliferation. / By KARIN E. BORNFELDT ; ELAINE W. RAINES ; LEE M. GRAVES ; MICHAEL P. SKINNER ; EDWIN G. KREBS ; RUSSELL Ross = 416
• Thrombin and Its Receptor in Growth Control. / By ELLEN VAN OBBERGHEN-SCHILLING ; VAL$$\acute E$$RIE VOURET-CRAVIARI ; YAO-HUI CHEN ; DOMINIQUE GRALL ; JEAN-CLAUDE CHAMBARD ; JACQUES POUYSS$$\acute E$$GUR = 431
• Structural and Functional Properties of the TRK Family of Neurotrophin Receptors. / By MARIANO BARBACID = 442
• Protein Kinase C Mediates Short- and Long-term Effects on Receptor Tyrosine Kinases: Regulation of Tyrosine Phosphorylation and Degradation. / By KLAUS SEEDORF ; MARK SHERMAN ; AXEL ULLRICH = 459
• Flag-Insulin Receptor Mutants. / By H. JOSEPH GOREN = 463
• Localization of Specific Amino Acids Contributing to Insulin Specificity of the Insulin Receptor. / By ASSER S. ANDERSEN ; FINN C. WIBERG ; THOMAS KJELDSEN = 466
• The Acute Insulin-like Effects of Growth Hormone in Primary Adipocyte-signaling Mechanisms. / By HANS TORNQVIST ; MARTIN RIDDERSTR$$\AA$$LE ; HANS ERIKSSON ; EVA DEGERMAN = 469
• Regulatory Interaction between Calmodulin and the Epidermal Growth Factor Receptor. / By ALBERTO BENGUR$$\acute I$$A ; JOS$$\acute E$$ MART$$\acute I$$N-NIETO ; GUSTAVO BENAIM ; ANTONIO VILLALOBO = 472
• Phosphorylation of Connexin-32 by the Epidermal Growth Factor Receptor Tyrosine Kinase. / By JUAN ANTONIO D$$\acute I$$EZ ; MARIBEL ELVIRA ; ANTONIO VILLALOBO = 477
• Molecular Dissection of the Growth Hormone Receptor: Identification of Distinct Cytoplasmic Domains Corresponding to Different Signaling Pathways. / By J. H. NIELSEN ; N. BILLESTRUP ; G. ALLEVATO ; A. M$$\phi$$LDRUP ; E. D. PETERSEN ; J. AMSTRUP ; J. A. HANSEN ; C. SVENSSON = 481
• Endothelin Stimulates MAP Kinase Activity and Protein Synthesis in Isolated Adult Feline Cardiac Myocytes. / By LINDA G. JONES ; KATRINA C. GAUSE ; KATHRYN E. MEIER = 484
• Index of Contributors = 487