로마 기준 IV 이해하기: 식도 질환 = Understanding the Rome IV: Esophageal Disorders

다국어 초록 (Multilingual Abstract)

The Rome IV criteria, published in 2016, encompass upper gastrointestinal lesions of functional esophageal disorders and func-tional gastroduodenal disorders. Functional esophageal disorders include functional chest pain, functional heartburn, reflux hyper-sensitivity, globus, and functional dysphagia. Patients with functional esophageal disorders typically have esophageal symptoms that are not associated with structural, inflammatory, or major esophageal motor disorders. Although the mechanisms of symptom generation in functional esophageal disorders are unclear, visceral hypersensitivity and hypervigilance may play a role. Therefore, treatment options include drugs and modalities that affect peripheral triggering and central perception. Further well-designed stud-ies are needed to identify the mechanisms of symptom generation in, and to develop appropriate therapies for, functional esophageal disorders. (Korean J Med 2017;92:354-361)

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