정제 코팅기의 분사펌프 유량제어시스템 설계

다국어 초록 (Multilingual Abstract)

With the development of pharmaceutical technology, many new medicines are being developed and marketed by spraying the main ingredient in the coating process to extend the duration of effect and reduce medicine intake, increasing the importance of the coating process in the tablet manufacturing process. In order to improve the coating quality of tablets, the spray pump control method was changed from a simple speed control method to a speed control method using a flow meter to spray at a constant flow rate without changing the flow rate due to deformation of the peristaltic pump tube due to long-term spray, and the spray pump flow rate was changed to a speed control method using a flow meter. This thesis presents a design method for a tablet coating spray pump flow control system. Through this study, design, and experiment, it is hoped that when using a Coriolis flow meter used for precise flow control, it will help to check the viscosity of the solution used and optimize the viscosity and spray time. It is hoped that this thesis's design, manufacture, and demonstration tests of the tablet coating process will improve the quality of the tablet coating, reduce the setting time and working time of the coating solution spray parameter, and help human health. * A thesis for the degree of Master in February 2024.

목차 (Table of Contents)

• Ⅰ. 서 론 1
• 1.1 연구의 배경과 필요성 1
• 1.2 연구내용 3
• II. 제약공장에서의 공정관리와 유량제어 현황 및 문제점 4
• 2.1 제약공장 정제 제조공정의 품질관리 4
• 2.2 제약공장의 제조공정관리 7
• 2.3 제약공장의 포장공정관리 8
• 2.4 정제 제조 코팅공정과 주요변수 10
• 2.5 코리올리 유량계 원리 및 특징 15
• 2.6 연동펌프의 원리 및 특징 17
• III. 정제 코팅기의 분사펌프 유량제어시스템 설계 20
• 3.1 분사펌프 유량제어시스템 전기제어 설계 20
• 3.2 분사펌프 유량제어시스템 기계, 기구 설계 27
• IV. 검증 및 고찰 30
• 4.1 유량제어시스템 제작 30
• 4.2 실증시험 32
• 4.2.1 실증시험조건 32
• 4.2.2 실증시험절차 32
• 4.2.3 실험결과 33
• 4.3 결과 고찰 39
• V. 결 론 41
• 참고문헌 42
• 부록 43