1 Quintiliani R, "Using pharmacodynamic and pharmacokinetic concepts to optimize treatment of infectious diseases" 21 : 219-232, 2004
2 Andriole VT, "The quinolones: past, present, and future" 41 (41): S113-S119, 2005
3 O'Donnell JA, "The newer fluoroquinolones" 18 : 691-716, 2004
4 Johnson RD, "The effect of sparfioxacin on the pharmacokinetics of theophylline at steady-state conditions" 35 : 936-, 1995
5 Mehlhorn AJ, "Safety concerns with fluoroquinolones" 41 : 1859-1866, 2007
6 Montay G, "Pharmacokinetics of sparfloxacin in humans after single oral administration at doses of 200, 400, 600, and 800mg" 34 : 1071-1076, 1994
7 Dandekar PK, "Pharmacokinetics of meropenem 0.5 and 2 g every 8 hours as a 3-hour infusion" 23 : 988-991, 2003
8 Nakashima M, "Pharmacokinetics and tolerance of DU-6859a, a new fluoroquinolone, after single and multiple oral doses in healthy volunteers" 39 : 170-174, 1995
9 Child J, "Pharmacokinetics and tissue penetration of the new fluoroquinolone grepafloxacin" 39 : 513-515, 1995
10 Teng R, "Pharmacokinetics and safety of trovafloxacin (CP-99,219), a new quinolone antibiotic, following administration of single oral doses to healthy male volunteers" 36 : 385-394, 1995
1 Quintiliani R, "Using pharmacodynamic and pharmacokinetic concepts to optimize treatment of infectious diseases" 21 : 219-232, 2004
2 Andriole VT, "The quinolones: past, present, and future" 41 (41): S113-S119, 2005
3 O'Donnell JA, "The newer fluoroquinolones" 18 : 691-716, 2004
4 Johnson RD, "The effect of sparfioxacin on the pharmacokinetics of theophylline at steady-state conditions" 35 : 936-, 1995
5 Mehlhorn AJ, "Safety concerns with fluoroquinolones" 41 : 1859-1866, 2007
6 Montay G, "Pharmacokinetics of sparfloxacin in humans after single oral administration at doses of 200, 400, 600, and 800mg" 34 : 1071-1076, 1994
7 Dandekar PK, "Pharmacokinetics of meropenem 0.5 and 2 g every 8 hours as a 3-hour infusion" 23 : 988-991, 2003
8 Nakashima M, "Pharmacokinetics and tolerance of DU-6859a, a new fluoroquinolone, after single and multiple oral doses in healthy volunteers" 39 : 170-174, 1995
9 Child J, "Pharmacokinetics and tissue penetration of the new fluoroquinolone grepafloxacin" 39 : 513-515, 1995
10 Teng R, "Pharmacokinetics and safety of trovafloxacin (CP-99,219), a new quinolone antibiotic, following administration of single oral doses to healthy male volunteers" 36 : 385-394, 1995
11 Stein GE, "Pharmacokinetics and pharmacodynamics of newer fluoroquinolones" 23 (23): S19-S24, 1996
12 Johnson JH, "Pharmacokinetics and inflammatory fluid penetration of sparfloxacin" 36 : 2444-2446, 1992
13 Craig WA, "Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men" 26 : 1-10, 1998
14 MacGowan AP, "Pharmacodynamics of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model of infection" 45 : 2916-2921, 2001
15 Child J, "Open-label crossover study to determine pharmacokinetics and penetration of two dose regimens of levofloxacin into inflammatory fluid" 39 : 2749-2751, 1995
16 Tanaka M, "Mechanistic study of inhibition of levofloxacin absorption by aluminum hydroxide" 37 : 2173-2178, 1993
17 Jacoby GA, "Mechanisms of resistance to quinolones" 41 (41): S120-S126, 2005
18 Davis R, "Levofloxacin. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacy" 47 : 677-700, 1994
19 Mueller M, "Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC" 48 : 369-377, 2004
20 Radandt JM, "Interactions of fluoroquinolones with other drugs: mechanisms, variability,clinical significance, and management" 14 : 272-284, 1992
21 Barton TD, "High rate of coadministration of di- or tri-valent cationcontaining compounds with oral fluoroquinolones: risk factors and potential implications" 26 : 93-99, 2005
22 Tanimura H, "Gallbladder tissue concentrations, biliary excretion and pharmacokinetics of OPC-17116" 49 (49): 341-343, 1995
23 Flor S, "Effects of magnesium-aluminum hydroxide and calcium carbonate antacids on bioavailability of ofloxacin" 34 : 2436-2438, 1990
24 Shiba K, "Effects of antacid on absorption and excretion of new quinolones" 49 (49): 360-361, 1995
25 Cohen KA, "Coadministration of oral levofloxacin with agents that impair absorption: impact on antibiotic resistance" 29 : 975-977, 2008
26 Ambrose PG, "Clinical pharmacodynamics of quinolones" 17 : 529-543, 2003
27 Wispelwey B, "Clinical implications of pharmacokinetics and pharmacodynamics of fluoroquinolones" 41 (41): S127-S135, 2005
28 Matsuda S, "Clinical experience with OPC-17116 in the treatment of gynaecological infections and its penetration into gynaecological tissues. Japanese Collaborative Study Group of OPC-17116 in Gynaecology" 49 (49): 395-398, 1995
29 Grant EM, "Clinical efficacy and pharmacoeconomics of a continuousinfusion piperacillin-tazobactam program in a large community teaching hospital" 22 : 471-483, 2002
30 Ball P, "Adverse drug reactions: implications for the development of fluoroquinolones" 51 (51): 21-27, 2003
31 Borner K, "A metabolite of sparfloxacin in urine" 45 (45): S303-S304, 1993