Combelen 처리가 축우의 유혈중 혈액상 , 혈액화학치 및 혈청 cortisol 농도에 미치는 영향 = The Effect of Combelen Administration on the Blood Picture , Blood Chemical Value and Serum Cortisol Concentration in Calves

다국어 초록 (Multilingual Abstract)

Two experiments were performed to investigate the changes in blood pictures, blood chemical values and serum cortisol concentration according to Combelen administration(Exp. 1, 2). Sixteen Holstein male calves of 5∼10 month-old(weighing 150 to 380 kg) were used. Each experiment was composed of four calves for experimental groups and control groups. In Exp. 1 and Exp. 2, each animal of experimental group was injected Combelen(N-(3`-dimethyl-aminop-ropyl) 3-propionyl phenothiazine l% solution) with intramusculary as level of 3ml/100kg or 2ml/100kg live body weight, respectively. The animals in control group of Exp. 1 and Exp. 2 were given saline administration instead of Combelen. The blood samples were collected just before and 2, 6 and 24 hours after treatment. The results obtained were summarized as follows; 1. There were no changes in erythrocytic blood values except the PCV according to quantity of Combelen and age of calves in Combelen administration. The PCV decreased(p $lt;.05) at 2∼6 hours after administration of Combelen. 2. The total leukocytes and differential leukocyte showed no noticeable change compared with control group. 3. The serum total protein showed a tendency to decrease at 2 hours after administration of Combelen, but A/G ratio was not changed. The blood glucose level had a tendency to increase at 2-6 hours after administration of Combelen, but BUN value showed a tendency to decrease at the same hours. 4. The serum cortisol concentration was not significantly changed after administration of Combelen, but there was slightly increased at 6 hours after injection compared with control group.