아로니아 베리 열매 및 잎 추출물의 항산화 활성 = Antioxidative Activities of Aronia melanocarpa Fruit and Leaf Extracts

다국어 초록 (Multilingual Abstract)

In this study, the antioxidative effects of Aronia melanocarpa fruit and leaf extracts were investigated. The free radical (1,1-diphenyl-2-picrylhydrazyl, DPPH) scavenging activities (FSC₅₀) of the ethylacetate and aglycone fractions of fruit extracts were 16.29 μg/mL, and 12.29 μg/mL, respectively. The free radical scavenging activity of fruit extract was higher than that of leaf extracts. Reactive oxygen species (ROS) scavenging activities (OSC₅₀) of the ethylacetate and aglycone fractions of fruit extracts on ROS generated in Fe³⁺-EDTA/H₂O₂ system using the luminol-dependent chemiluminescence assay showed 2.86 μg/mL, and 1.80 μg/mL, respectively. ROS scavenging activity of the aglycone fraction of fruit extracts was similar to that of L-ascorbic acid (1.50 μg/mL). The ROS scavenging activity of fruit extracts was higher than that of leaf extracts. The cellular protective effects of aglycone fraction of fruit extracts (τ₅₀ = 72.3 min) on the ¹O₂-induced cellular damage of human erythrocytes especially were increased in a concentration dependent manner (5 ~ 50 μg/mL). τ₅₀ (72.3 min) of the aglycone fraction showed 1.9 times higher than (+)-α -tocopherol (38 min), known as lipophilic antioxidant at 10 μg/mL. These results incidicate that A. melanocarpa fruit extracts have higher antioxidant effects than leaf extracts and could be applicable to functional cosmetics materials for antioxidants by protecting skin exposed to solar UV radiation against ROS including ¹O₂.

참고문헌 (Reference)

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