Polyphenol and vitamin C are known to prevent lipid peroxidation during exercise. Among the known polyphenol, the polyphenol extracted from apple as used has the similar effect of antioxidant. Therefore we examined the effects of acute or chronic poly...
Polyphenol and vitamin C are known to prevent lipid peroxidation during exercise. Among the known polyphenol, the polyphenol extracted from apple as used has the similar effect of antioxidant. Therefore we examined the effects of acute or chronic polyphenol or vitamin C on antioxidants enzymes activities in rats. Rats were exercise training on the treadmill before 3 d of sacrifice for treadmill adaptation. They were administered 5 % of polyphenol and 50㎎ of vitamin C before the exercise at the final day of the experiment in acute administration group (APA or AVA) and the same amount of supplements was administered for 4 wk (CPA or CVA). Control group was administered the same amount of water at the same time point (NA). One-way ANOVA was performed as the statistical analysis. MDA concentrations in liver, heart, soleus muscle, gastrocnemius red and white muscle were significantly decreased by polyphenol or vitamin C administration. In addition, chronic administration has the strong effect compared with acute administration SOD concentrations in liver and heart were significantly increased by polyphenol or vitamin C administration. However, skeletal muscle SOD concentrations were not statistically significant. These results suggested that endurance exercise training reduced the risk of lipid peroxidation during exercise in rats. Moreover, acute or chronic administration of polyphenol and vitamin C increased the antioxidative activity that prevent the lipid peroxidation during exercise in rats.